ID   LPFD_ECO57              Reviewed;         351 AA.
AC   Q8X5K9; Q7A9Y9;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Probable minor fimbrial subunit LpfD;
DE   Flags: Precursor;
GN   Name=lpfD; OrderedLocusNames=Z4966, ECs4427;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [3]
RP   FUNCTION, INDUCTION, AND GENE NAME.
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=12228266; DOI=10.1128/iai.70.10.5416-5427.2002;
RA   Torres A.G., Giron J.A., Perna N.T., Burland V., Blattner F.R.,
RA   Avelino-Flores F., Kaper J.B.;
RT   "Identification and characterization of lpfABCC'DE, a fimbrial operon of
RT   enterohemorrhagic Escherichia coli O157:H7.";
RL   Infect. Immun. 70:5416-5427(2002).
CC   -!- FUNCTION: Part of the lpfABCC'DE fimbrial operon. LP fimbriae may
CC       participate in the interaction with eukaryotic cells by assisting in
CC       microcolony formation. {ECO:0000269|PubMed:12228266}.
CC   -!- SUBCELLULAR LOCATION: Fimbrium {ECO:0000250}.
CC   -!- INDUCTION: Induced during the exponential growth phase.
CC       {ECO:0000269|PubMed:12228266}.
CC   -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG58691.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37850.1; -; Genomic_DNA.
DR   PIR; C91182; C91182.
DR   PIR; G86028; G86028.
DR   RefSeq; NP_312454.1; NC_002695.1.
DR   RefSeq; WP_000642260.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X5K9; -.
DR   SMR; Q8X5K9; -.
DR   STRING; 155864.EDL933_4807; -.
DR   EnsemblBacteria; AAG58691; AAG58691; Z4966.
DR   EnsemblBacteria; BAB37850; BAB37850; ECs_4427.
DR   GeneID; 915705; -.
DR   KEGG; ece:Z4966; -.
DR   KEGG; ecs:ECs_4427; -.
DR   PATRIC; fig|386585.9.peg.4633; -.
DR   eggNOG; COG3539; Bacteria.
DR   HOGENOM; CLU_066608_0_0_6; -.
DR   OMA; ATMHVEL; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR000259; Adhesion_dom_fimbrial.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   Pfam; PF00419; Fimbrial; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   2: Evidence at transcript level;
KW   Fimbrium; Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..351
FT                   /note="Probable minor fimbrial subunit LpfD"
FT                   /id="PRO_0000429481"
SQ   SEQUENCE   351 AA;  37239 MW;  2C4A4DDA1523CBF1 CRC64;
     MKAAIALSLL GCVFGFSGKA FAGDAWGPCT PADGTTYHYN VDVDVGIPDA AKNVAGTVLP
     DVLNWSNGQN VSLICECPDS YKNEKDTLVQ GVSMLPPSGR TVDSMKYYTL TEELEVATNI
     RISTSVYGFV PFKNQQALQT TGCNKVITTP YMGGAGLLSF AITKPFIGDS VIPLTLIAEL
     YASKTNKDYG TIPISSVSIQ GRVTVTQDCE IKPGTVLDVP FGEFPSSAFK NRQGQMPEGA
     TEQEINLSFD CNNISDGIKV ALRLEGATNA DDPRAVDMGN PDIGVLVKDS SGKILVPNDS
     SSTTLLNLSS LDSKTHRNAA IRLLALPIST TGKAPKGGTF EGVTTIYLEM E