ID   LPFE_ECO57              Reviewed;         176 AA.
AC   Q8X5L0; Q7A9Z0;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Probable fimbrial subunit LpfE;
DE   Flags: Precursor;
GN   Name=lpfE; OrderedLocusNames=Z4965, ECs4426;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [3]
RP   FUNCTION, INDUCTION, AND GENE NAME.
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=12228266; DOI=10.1128/iai.70.10.5416-5427.2002;
RA   Torres A.G., Giron J.A., Perna N.T., Burland V., Blattner F.R.,
RA   Avelino-Flores F., Kaper J.B.;
RT   "Identification and characterization of lpfABCC'DE, a fimbrial operon of
RT   enterohemorrhagic Escherichia coli O157:H7.";
RL   Infect. Immun. 70:5416-5427(2002).
CC   -!- FUNCTION: Part of the lpfABCC'DE fimbrial operon. LP fimbriae may
CC       participate in the interaction with eukaryotic cells by assisting in
CC       microcolony formation. {ECO:0000269|PubMed:12228266}.
CC   -!- SUBCELLULAR LOCATION: Fimbrium {ECO:0000250}.
CC   -!- INDUCTION: Induced during the exponential growth phase.
CC       {ECO:0000269|PubMed:12228266}.
CC   -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG58690.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37849.1; -; Genomic_DNA.
DR   PIR; B91182; B91182.
DR   PIR; F86028; F86028.
DR   RefSeq; NP_312453.1; NC_002695.1.
DR   RefSeq; WP_000669675.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X5L0; -.
DR   SMR; Q8X5L0; -.
DR   STRING; 155864.EDL933_4806; -.
DR   EnsemblBacteria; AAG58690; AAG58690; Z4965.
DR   EnsemblBacteria; BAB37849; BAB37849; ECs_4426.
DR   GeneID; 915704; -.
DR   KEGG; ece:Z4965; -.
DR   KEGG; ecs:ECs_4426; -.
DR   PATRIC; fig|386585.9.peg.4632; -.
DR   eggNOG; COG3539; Bacteria.
DR   HOGENOM; CLU_088965_0_3_6; -.
DR   OMA; GHANAMV; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR000259; Adhesion_dom_fimbrial.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   Pfam; PF00419; Fimbrial; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   2: Evidence at transcript level;
KW   Fimbrium; Reference proteome; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..176
FT                   /note="Probable fimbrial subunit LpfE"
FT                   /id="PRO_0000429483"
SQ   SEQUENCE   176 AA;  18475 MW;  F7FAECD07BFAAAA9 CRC64;
     MKFKRLLHSG IASLSLVACG VNAATDLGPA GDIHFSITIT TKACEMEKSD LEVDMGTMTL
     QKPAAVGTVL SKKDFTIELK ECDGISKATV EMDSQSDSDD DSMFALEAGG ATGVALKIED
     DKGTQQVPKG SSGTPIEWAI DGETTSLHYQ ASYVVVNTQA TGGTANALVN FSITYE