LPFUR_ECOLI
ID LPFUR_ECOLI Reviewed; 28 AA.
AC A8DYP9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-NOV-2007, sequence version 1.
DT 03-AUG-2022, entry version 45.
DE RecName: Full=fur leader peptide;
GN Name=uof; OrderedLocusNames=b4637;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP FUNCTION IN TRANSLATION OF FUR, AND INDUCTION.
RX PubMed=17268550; DOI=10.1038/sj.emboj.7601553;
RA Vecerek B., Moll I., Blaesi U.;
RT "Control of Fur synthesis by the non-coding RNA RyhB and iron-responsive
RT decoding.";
RL EMBO J. 26:965-975(2007).
CC -!- FUNCTION: Cotranscribed with fur, it is essential for fur translation.
CC The fur ribosomal binding site (RBS) is occluded by the 5'-mRNA
CC secondary structure, which is opened by uof translation.
CC {ECO:0000269|PubMed:17268550}.
CC -!- INDUCTION: By iron depletion. Repressed by the ncRNA ryhB.
CC {ECO:0000269|PubMed:17268550}.
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DR EMBL; U00096; ABV59574.1; -; Genomic_DNA.
DR RefSeq; WP_001406816.1; NZ_STEB01000044.1.
DR RefSeq; YP_001491546.1; NC_000913.3.
DR AlphaFoldDB; A8DYP9; -.
DR STRING; 511145.b4637; -.
DR PRIDE; A8DYP9; -.
DR EnsemblBacteria; ABV59574; ABV59574; b4637.
DR GeneID; 5625562; -.
DR GeneID; 67413731; -.
DR KEGG; eco:b4637; -.
DR PATRIC; fig|83333.103.peg.1454; -.
DR BioCyc; EcoCyc:MON0-2801; -.
DR PRO; PR:A8DYP9; -.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0006417; P:regulation of translation; IDA:EcoCyc.
PE 1: Evidence at protein level;
KW Leader peptide; Reference proteome.
FT PEPTIDE 1..28
FT /note="fur leader peptide"
FT /id="PRO_0000315217"
SQ SEQUENCE 28 AA; 3109 MW; 3A799921ABC715B4 CRC64;
MIRIISRANS VTSSNEVNRL VTGQIPHD