ID   LPHI_SALTY              Reviewed;          16 AA.
AC   P60997; P03058;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=his operon leader peptide;
DE   AltName: Full=his operon attenuator peptide;
GN   Name=hisL; OrderedLocusNames=STM2070.1;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=360216; DOI=10.1073/pnas.75.9.4281;
RA   Barnes W.M.;
RT   "DNA sequence from the histidine operon control region: seven histidine
RT   codons in a row.";
RL   Proc. Natl. Acad. Sci. U.S.A. 75:4281-4285(1978).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=3062174; DOI=10.1016/0022-2836(88)90194-5;
RA   Carlomagno M.S., Chiariotti L., Alifano P., Nappo A.G., Bruni C.B.;
RT   "Structure and function of the Salmonella typhimurium and Escherichia coli
RT   K-12 histidine operons.";
RL   J. Mol. Biol. 203:585-606(1988).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RA   Barnes W.M., Husson R.N., Whittier R.;
RL   Submitted (AUG-1989) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: This protein is involved in the attenuation mechanism for the
CC       control of the expression of the his operon structural genes.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the HisL family. {ECO:0000305}.
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DR   EMBL; V01371; CAA24656.1; -; Genomic_DNA.
DR   EMBL; X13464; CAA31821.1; -; Genomic_DNA.
DR   EMBL; J01804; AAA88613.1; -; Genomic_DNA.
DR   EMBL; AE006468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; P60997; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR012565; His_leader.
DR   Pfam; PF08047; His_leader; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Histidine biosynthesis; Leader peptide;
KW   Reference proteome.
FT   PEPTIDE         1..16
FT                   /note="his operon leader peptide"
FT                   /id="PRO_0000043991"
SQ   SEQUENCE   16 AA;  2081 MW;  C8B7907BF6283BBA CRC64;
     MTRVQFKHHH HHHHPD