LPIV_ECOLI
ID LPIV_ECOLI Reviewed; 32 AA.
AC P03061; Q2M7Y5;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=ilv operon leader peptide;
DE AltName: Full=ilvBN operon attenuator peptide;
GN Name=ivbL; OrderedLocusNames=b3672, JW3647;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=6292893; DOI=10.1073/pnas.79.20.6156;
RA Friden P., Newman T., Freundlich M.;
RT "Nucleotide sequence of the ilvB promoter-regulatory region: a biosynthetic
RT operon controlled by attenuation and cyclic AMP.";
RL Proc. Natl. Acad. Sci. U.S.A. 79:6156-6160(1982).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2989782; DOI=10.1093/nar/13.11.3995;
RA Wek R.C., Hausser C.A., Hatfield G.W.;
RT "The nucleotide sequence of the ilvBN operon of Escherichia coli: sequence
RT homologies of the acetohydroxy acid synthase isozymes.";
RL Nucleic Acids Res. 13:3995-4010(1985).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=7686882; DOI=10.1006/geno.1993.1230;
RA Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.;
RT "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome:
RT organizational symmetry around the origin of replication.";
RL Genomics 16:551-561(1993).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: This protein is involved in control of the biosynthesis of
CC isoleucine, leucine, and valine.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X02541; CAA26386.1; -; Genomic_DNA.
DR EMBL; L10328; AAA62024.1; -; Genomic_DNA.
DR EMBL; U00096; AAC76695.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77621.1; -; Genomic_DNA.
DR PIR; A03597; LFECIV.
DR RefSeq; NP_418128.1; NC_000913.3.
DR RefSeq; WP_001300753.1; NZ_SSZK01000043.1.
DR AlphaFoldDB; P03061; -.
DR BioGRID; 4259302; 2.
DR STRING; 511145.b3672; -.
DR PaxDb; P03061; -.
DR PRIDE; P03061; -.
DR EnsemblBacteria; AAC76695; AAC76695; b3672.
DR EnsemblBacteria; BAE77621; BAE77621; BAE77621.
DR GeneID; 60902619; -.
DR GeneID; 948181; -.
DR KEGG; ecj:JW3647; -.
DR KEGG; eco:b3672; -.
DR EchoBASE; EB1253; -.
DR eggNOG; ENOG5031KVZ; Bacteria.
DR HOGENOM; CLU_218700_0_1_6; -.
DR BioCyc; EcoCyc:EG11275-MON; -.
DR PRO; PR:P03061; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009099; P:valine biosynthetic process; IMP:EcoCyc.
DR InterPro; IPR012566; IlvB_leader.
DR Pfam; PF08049; IlvB_leader; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis; Branched-chain amino acid biosynthesis;
KW Leader peptide; Reference proteome.
FT PEPTIDE 1..32
FT /note="ilv operon leader peptide"
FT /id="PRO_0000044761"
SQ SEQUENCE 32 AA; 3206 MW; 7CD58DCCBD336ECF CRC64;
MTTSMLNAKL LPTAPSAAVV VVRVVVVVGN AP
