ID   LPK1_LOCMI              Reviewed;          16 AA.
AC   P20404;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 3.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Locustapyrokinin-1;
DE   AltName: Full=Lom-PK-1;
OS   Locusta migratoria (Migratory locust).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Oedipodinae; Locusta.
OX   NCBI_TaxID=7004;
RN   [1]
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AND AMIDATION AT
RP   LEU-16.
RC   TISSUE=Corpora cardiaca;
RX   PubMed=2026322; DOI=10.1016/0016-6480(91)90129-t;
RA   Schoofs L., Holman G.M., Hayes T.K., Nachman R.J., de Loof A.;
RT   "Isolation, primary structure, and synthesis of locustapyrokinin: a
RT   myotropic peptide of Locusta migratoria.";
RL   Gen. Comp. Endocrinol. 81:97-104(1991).
CC   -!- FUNCTION: Mediates visceral muscle contractile activity (myotropic
CC       activity).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the pyrokinin family. {ECO:0000305}.
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DR   PIR; A49761; A49761.
DR   AlphaFoldDB; P20404; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR001484; Pyrokinin_CS.
DR   PROSITE; PS00539; PYROKININ; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide;
KW   Pyrrolidone carboxylic acid; Secreted.
FT   PEPTIDE         1..16
FT                   /note="Locustapyrokinin-1"
FT                   /id="PRO_0000044317"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:2026322"
FT   MOD_RES         16
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000269|PubMed:2026322"
SQ   SEQUENCE   16 AA;  1827 MW;  A7178BBDCA0AFDD6 CRC64;
     QDSGDGWPQQ PFVPRL