ID   LPLT_SALPK              Reviewed;         400 AA.
AC   B5BFH5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Lysophospholipid transporter LplT {ECO:0000255|HAMAP-Rule:MF_01585};
GN   Name=lplT {ECO:0000255|HAMAP-Rule:MF_01585}; OrderedLocusNames=SSPA2679;
OS   Salmonella paratyphi A (strain AKU_12601).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=554290;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AKU_12601;
RX   PubMed=19159446; DOI=10.1186/1471-2164-10-36;
RA   Holt K.E., Thomson N.R., Wain J., Langridge G.C., Hasan R., Bhutta Z.A.,
RA   Quail M.A., Norbertczak H., Walker D., Simmonds M., White B., Bason N.,
RA   Mungall K., Dougan G., Parkhill J.;
RT   "Pseudogene accumulation in the evolutionary histories of Salmonella
RT   enterica serovars Paratyphi A and Typhi.";
RL   BMC Genomics 10:36-36(2009).
CC   -!- FUNCTION: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-
CC       phosphoethanolamine (2-acyl-GPE) into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01585}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01585}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01585}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. LplT (TC
CC       2.A.1.42) family. {ECO:0000255|HAMAP-Rule:MF_01585}.
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DR   EMBL; FM200053; CAR60920.1; -; Genomic_DNA.
DR   RefSeq; WP_000004686.1; NC_011147.1.
DR   AlphaFoldDB; B5BFH5; -.
DR   SMR; B5BFH5; -.
DR   KEGG; sek:SSPA2679; -.
DR   HOGENOM; CLU_047399_0_0_6; -.
DR   OMA; ICFGFNP; -.
DR   Proteomes; UP000001869; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051978; F:lysophospholipid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   HAMAP; MF_01585; MFS_LplT; 1.
DR   InterPro; IPR023727; LysoPLipid__transptr_LplT.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Lipid transport; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..400
FT                   /note="Lysophospholipid transporter LplT"
FT                   /id="PRO_1000201279"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        195..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        281..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        352..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        373..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
SQ   SEQUENCE   400 AA;  41571 MW;  897D9BA08496F7D5 CRC64;
     MSESVRTNTS IWSKGMLSVI VAQFLSAFGD NALLFATLAL LKAQFYPDWS QPVLQMVFVG
     AYILFAPFVG QIADSFAKGR VMMVANGLKL AGAAGICLGV NPFVGYTLVG IGAAAYSPAK
     YGILGELTTG DKLVKANGLM EASTIAAILL GSVAGGVLAD WHVIAALVAC ALAYAGAVAA
     NLFIPKLVAA RPGQSWRLSA MTRSFFSACV VLWRNGETRF SLVGTGLFWG AGVTLRFLLV
     LWVPVALGIT DNATPTYLNA MVAVGIVVGA GAAAKLVTLE TVSRCMPAGI LIGVVVAIFS
     LQHALLPAYA LLLLIGMLGG FFVVPLNALL QERGKKSVGA GNAIAVQNLG ENSAMLLMLG
     LYSLAVLVGV PAVAIGIGFG VLFALAIAAL WIWQRRQASY