ID   LPLT_YERPP              Reviewed;         406 AA.
AC   A4TLD2;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Lysophospholipid transporter LplT {ECO:0000255|HAMAP-Rule:MF_01585};
GN   Name=lplT {ECO:0000255|HAMAP-Rule:MF_01585}; OrderedLocusNames=YPDSF_1709;
OS   Yersinia pestis (strain Pestoides F).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=386656;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pestoides F;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Di Bartolo G., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Worsham P., Chu M., Bearden S., Garcia E.,
RA   Richardson P.;
RT   "Complete sequence of chromosome of Yersinia pestis Pestoides F.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-
CC       phosphoethanolamine (2-acyl-GPE) into the cell. {ECO:0000255|HAMAP-
CC       Rule:MF_01585}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01585}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01585}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. LplT (TC
CC       2.A.1.42) family. {ECO:0000255|HAMAP-Rule:MF_01585}.
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DR   EMBL; CP000668; ABP40094.1; -; Genomic_DNA.
DR   RefSeq; WP_002209842.1; NZ_CP009715.1.
DR   AlphaFoldDB; A4TLD2; -.
DR   SMR; A4TLD2; -.
DR   GeneID; 66844527; -.
DR   KEGG; ypp:YPDSF_1709; -.
DR   PATRIC; fig|386656.14.peg.2051; -.
DR   OMA; ICFGFNP; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051978; F:lysophospholipid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   HAMAP; MF_01585; MFS_LplT; 1.
DR   InterPro; IPR023727; LysoPLipid__transptr_LplT.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Lipid transport; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..406
FT                   /note="Lysophospholipid transporter LplT"
FT                   /id="PRO_0000309843"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        164..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        310..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01585"
SQ   SEQUENCE   406 AA;  42841 MW;  75DC17EBEC1D1FDE CRC64;
     MSQDVLADKP LLSRSMVAVL CAQFFSAFGD NALLFATLAL IKQQLYPDWS QPILQMAFVA
     TYIVLAPFVG QIADGFAKGR VMMVANGLKL AGALVICFGL NPFLGYSLVG VGAAAYSPAK
     YGILGEITSG EQLVKANGMM EASTIAAILL GSVAGGILAD WHLMAALGVC ALVYAIAVIA
     NLFIPRLAAA RSGASWRPRA MTGSFFTACR LLWQDSETRF SLAGTSLFWG AGVTLRFLLV
     LWVPVALGIA DNATPTLLNA MVAIGIVVGA GAAARFVTLK TVKRCLPAGV LIGVMVTIFS
     LQNSMPMAYL LLIIIGILGG FFVVPLNALL QERGKHSVGA GNAIAVQNLG ENTAMLFMLG
     LYSLVVKLGA PVVAVGVGFG VVFALAIALL WGWQWRQQRQ KTRQPE