ID   LPL_ECO57               Reviewed;          28 AA.
AC   P0AD81; P09149; Q8VSS2; Q8VSS3;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=leu operon leader peptide;
DE   AltName: Full=leu operon attenuator peptide;
GN   Name=leuL; OrderedLocusNames=Z0084, ECs0079;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19.
RC   STRAIN=O157:H7 / Au1808 / EHEC, and O157:H7 / Au6 / EHEC;
RX   PubMed=11698378; DOI=10.1128/jb.183.23.6885-6897.2001;
RA   Kim J., Nietfeldt J.W., Ju J., Wise J., Fegan N., Desmarchelier P.,
RA   Benson A.K.;
RT   "Ancestral divergence, genome diversification, and phylogeographic
RT   variation in subpopulations of sorbitol-negative, beta-glucuronidase-
RT   negative enterohemorrhagic Escherichia coli O157.";
RL   J. Bacteriol. 183:6885-6897(2001).
CC   -!- FUNCTION: Involved in control of the biosynthesis of leucine.
CC       {ECO:0000250}.
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DR   EMBL; AE005174; AAG54379.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB33502.1; -; Genomic_DNA.
DR   EMBL; AF368048; AAL38430.1; -; Genomic_DNA.
DR   EMBL; AF368047; AAL38429.1; -; Genomic_DNA.
DR   PIR; G85489; G85489.
DR   PIR; G90638; G90638.
DR   RefSeq; NP_308106.1; NC_002695.1.
DR   RefSeq; WP_001300467.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AD81; -.
DR   EnsemblBacteria; AAG54379; AAG54379; Z0084.
DR   EnsemblBacteria; BAB33502; BAB33502; ECs_0079.
DR   GeneID; 67416148; -.
DR   GeneID; 913517; -.
DR   KEGG; ece:Z0084; -.
DR   KEGG; ecs:ECs_0079; -.
DR   PATRIC; fig|83334.175.peg.217; -.
DR   HOGENOM; CLU_221572_0_0_6; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR012570; Leu_leader.
DR   Pfam; PF08054; Leu_leader; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Branched-chain amino acid biosynthesis;
KW   Leader peptide; Leucine biosynthesis; Reference proteome.
FT   PEPTIDE         1..28
FT                   /note="leu operon leader peptide"
FT                   /id="PRO_0000043996"
FT   VARIANT         13
FT                   /note="L -> LL (in strain: AU1808)"
SQ   SEQUENCE   28 AA;  3146 MW;  63914DFFD94E122E CRC64;
     MTHIVRFIGL LLLNASSLRG RRVSGIQH