ID   LPL_ECOLI               Reviewed;          28 AA.
AC   P0AD79; P09149; Q8VSS2; Q8VSS3;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=leu operon leader peptide;
DE   AltName: Full=leu operon attenuator peptide;
GN   Name=leuL; Synonyms=leuLP; OrderedLocusNames=b0075, JW0074;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=6171647; DOI=10.1016/0022-2836(81)90348-x;
RA   Wessler S.R., Calvo J.M.;
RT   "Control of leu operon expression in Escherichia coli by a transcription
RT   attenuation mechanism.";
RL   J. Mol. Biol. 149:579-597(1981).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=1630901; DOI=10.1093/nar/20.13.3305;
RA   Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N., Isono K.,
RA   Mizobuchi K., Nakata A.;
RT   "Systematic sequencing of the Escherichia coli genome: analysis of the 0-
RT   2.4 min region.";
RL   Nucleic Acids Res. 20:3305-3308(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Involved in control of the biosynthesis of leucine.
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DR   EMBL; J01642; AAA24065.1; -; Genomic_DNA.
DR   EMBL; X55034; CAA38852.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC73186.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAB96644.1; -; Genomic_DNA.
DR   PIR; A30376; LFECL.
DR   RefSeq; NP_414617.1; NC_000913.3.
DR   RefSeq; WP_001300467.1; NZ_STEB01000010.1.
DR   AlphaFoldDB; P0AD79; -.
DR   STRING; 511145.b0075; -.
DR   PaxDb; P0AD79; -.
DR   PRIDE; P0AD79; -.
DR   EnsemblBacteria; AAC73186; AAC73186; b0075.
DR   EnsemblBacteria; BAB96644; BAB96644; BAB96644.
DR   GeneID; 67416148; -.
DR   GeneID; 946072; -.
DR   KEGG; ecj:JW0074; -.
DR   KEGG; eco:b0075; -.
DR   PATRIC; fig|83333.103.peg.820; -.
DR   EchoBASE; EB1257; -.
DR   HOGENOM; CLU_221572_0_0_6; -.
DR   PhylomeDB; P0AD79; -.
DR   BioCyc; EcoCyc:EG11280-MON; -.
DR   PRO; PR:P0AD79; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR012570; Leu_leader.
DR   Pfam; PF08054; Leu_leader; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis; Branched-chain amino acid biosynthesis;
KW   Leader peptide; Leucine biosynthesis; Reference proteome.
FT   PEPTIDE         1..28
FT                   /note="leu operon leader peptide"
FT                   /id="PRO_0000043995"
SQ   SEQUENCE   28 AA;  3146 MW;  63914DFFD94E122E CRC64;
     MTHIVRFIGL LLLNASSLRG RRVSGIQH