LPMG_ECO57
ID LPMG_ECO57 Reviewed; 17 AA.
AC Q8X4G0;
DT 11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2011, sequence version 2.
DT 25-MAY-2022, entry version 65.
DE RecName: Full=mgtA leader peptide;
DE AltName: Full=Regulatory leader peptide for mgtA;
GN Name=mgtL; OrderedLocusNames=Z5852, ECs5218.1;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Makes mgtA transcription sensitive to intracellular proline
CC levels. Under low levels of proline this protein cannot be fully
CC translated, and a stem loop forms which permits transcription of the
CC downstream mgtA gene (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MgtL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG59439.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AE005174; AAG59439.1; ALT_INIT; Genomic_DNA.
DR EMBL; BA000007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; C86122; C86122.
DR RefSeq; WP_001387276.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; Q8X4G0; -.
DR EnsemblBacteria; AAG59439; AAG59439; Z5852.
DR GeneID; 67414865; -.
DR KEGG; ece:Z5852; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR InterPro; IPR031434; MGTL.
DR Pfam; PF17059; MGTL; 1.
PE 3: Inferred from homology;
KW Leader peptide; Reference proteome.
FT CHAIN 1..17
FT /note="mgtA leader peptide"
FT /id="PRO_0000403454"
SQ SEQUENCE 17 AA; 2123 MW; 0F46CE7376700551 CRC64;
MEPDPTPLPR RRLKLFR