LPMG_ECO5T
ID LPMG_ECO5T Reviewed; 17 AA.
AC C6UP45;
DT 11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2011, sequence version 2.
DT 25-MAY-2022, entry version 42.
DE RecName: Full=mgtA leader peptide;
DE AltName: Full=Regulatory leader peptide for mgtA;
GN Name=mgtL; OrderedLocusNames=ECSP_5343;
OS Escherichia coli O157:H7 (strain TW14359 / EHEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=544404;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TW14359 / EHEC;
RX PubMed=19564389; DOI=10.1128/iai.00198-09;
RA Kulasekara B.R., Jacobs M., Zhou Y., Wu Z., Sims E., Saenphimmachak C.,
RA Rohmer L., Ritchie J.M., Radey M., McKevitt M., Freeman T.L., Hayden H.,
RA Haugen E., Gillett W., Fong C., Chang J., Beskhlebnaya V., Waldor M.K.,
RA Samadpour M., Whittam T.S., Kaul R., Brittnacher M., Miller S.I.;
RT "Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-
RT associated outbreak isolate indicates candidate genes that may enhance
RT virulence.";
RL Infect. Immun. 77:3713-3721(2009).
CC -!- FUNCTION: Makes mgtA transcription sensitive to intracellular proline
CC levels. Under low levels of proline this protein cannot be fully
CC translated, and a stem loop forms which permits transcription of the
CC downstream mgtA gene (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MgtL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ACT75023.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; CP001368; ACT75023.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_001387276.1; NC_013008.1.
DR AlphaFoldDB; C6UP45; -.
DR GeneID; 67414865; -.
DR KEGG; etw:ECSP_5343; -.
DR HOGENOM; CLU_2896927_0_0_6; -.
DR InterPro; IPR031434; MGTL.
DR Pfam; PF17059; MGTL; 1.
PE 3: Inferred from homology;
KW Leader peptide.
FT CHAIN 1..17
FT /note="mgtA leader peptide"
FT /id="PRO_0000403455"
SQ SEQUENCE 17 AA; 2123 MW; 0F46CE7376700551 CRC64;
MEPDPTPLPR RRLKLFR