LPMG_ECOHS
ID LPMG_ECOHS Reviewed; 17 AA.
AC A8A7Z8;
DT 11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2011, sequence version 2.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=mgtA leader peptide;
DE AltName: Full=Regulatory leader peptide for mgtA;
GN Name=mgtL; OrderedLocusNames=EcHS_A4496;
OS Escherichia coli O9:H4 (strain HS).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=331112;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS;
RX PubMed=18676672; DOI=10.1128/jb.00619-08;
RA Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F.,
RA Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA Henderson I.R., Sperandio V., Ravel J.;
RT "The pangenome structure of Escherichia coli: comparative genomic analysis
RT of E. coli commensal and pathogenic isolates.";
RL J. Bacteriol. 190:6881-6893(2008).
CC -!- FUNCTION: Makes mgtA transcription sensitive to intracellular proline
CC levels. Under low levels of proline this protein cannot be fully
CC translated, and a stem loop forms which permits transcription of the
CC downstream mgtA gene (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MgtL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABV08652.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; CP000802; ABV08652.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_001387276.1; NC_009800.1.
DR AlphaFoldDB; A8A7Z8; -.
DR GeneID; 67414865; -.
DR KEGG; ecx:EcHS_A4496; -.
DR HOGENOM; CLU_2896927_0_0_6; -.
DR Proteomes; UP000001123; Chromosome.
DR InterPro; IPR031434; MGTL.
DR Pfam; PF17059; MGTL; 1.
PE 3: Inferred from homology;
KW Leader peptide.
FT CHAIN 1..17
FT /note="mgtA leader peptide"
FT /id="PRO_0000403458"
SQ SEQUENCE 17 AA; 2123 MW; 0F46CE7376700551 CRC64;
MEPDPTPLPR RRLKLFR