LPMG_ECOL5
ID LPMG_ECOL5 Reviewed; 17 AA.
AC Q0T9E7;
DT 11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2011, sequence version 2.
DT 25-MAY-2022, entry version 57.
DE RecName: Full=mgtA leader peptide;
DE AltName: Full=Regulatory leader peptide for mgtA;
GN Name=mgtL; OrderedLocusNames=ECP_4491;
OS Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=362663;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=536 / UPEC;
RX PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT "Role of pathogenicity island-associated integrases in the genome
RT plasticity of uropathogenic Escherichia coli strain 536.";
RL Mol. Microbiol. 61:584-595(2006).
CC -!- FUNCTION: Makes mgtA transcription sensitive to intracellular proline
CC levels. Under low levels of proline this protein cannot be fully
CC translated, and a stem loop forms which permits transcription of the
CC downstream mgtA gene (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MgtL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABG72432.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; CP000247; ABG72432.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_001387276.1; NC_008253.1.
DR AlphaFoldDB; Q0T9E7; -.
DR STRING; 362663.ECP_4491; -.
DR EnsemblBacteria; ABG72432; ABG72432; ECP_4491.
DR GeneID; 67414865; -.
DR KEGG; ecp:ECP_4491; -.
DR HOGENOM; CLU_2896927_0_0_6; -.
DR Proteomes; UP000009182; Chromosome.
DR InterPro; IPR031434; MGTL.
DR Pfam; PF17059; MGTL; 1.
PE 3: Inferred from homology;
KW Leader peptide.
FT CHAIN 1..17
FT /note="mgtA leader peptide"
FT /id="PRO_0000403457"
SQ SEQUENCE 17 AA; 2123 MW; 0F46CE7376700551 CRC64;
MEPDPTPLPR RRLKLFR