LPMG_ECOUT
ID LPMG_ECOUT Reviewed; 17 AA.
AC Q1R314;
DT 11-JAN-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-JAN-2011, sequence version 2.
DT 25-MAY-2022, entry version 53.
DE RecName: Full=mgtA leader peptide;
DE AltName: Full=Regulatory leader peptide for mgtA;
GN Name=mgtL; OrderedLocusNames=UTI89_C4846;
OS Escherichia coli (strain UTI89 / UPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=364106;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTI89 / UPEC;
RX PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S.,
RA Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J.,
RA Gordon J.I.;
RT "Identification of genes subject to positive selection in uropathogenic
RT strains of Escherichia coli: a comparative genomics approach.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
CC -!- FUNCTION: Makes mgtA transcription sensitive to intracellular proline
CC levels. Under low levels of proline this protein cannot be fully
CC translated, and a stem loop forms which permits transcription of the
CC downstream mgtA gene (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MgtL family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABE10250.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; CP000243; ABE10250.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_001387276.1; NC_007946.1.
DR AlphaFoldDB; Q1R314; -.
DR EnsemblBacteria; ABE10250; ABE10250; UTI89_C4846.
DR GeneID; 67414865; -.
DR KEGG; eci:UTI89_C4846; -.
DR HOGENOM; CLU_2896927_0_0_6; -.
DR Proteomes; UP000001952; Chromosome.
DR InterPro; IPR031434; MGTL.
DR Pfam; PF17059; MGTL; 1.
PE 3: Inferred from homology;
KW Leader peptide.
FT CHAIN 1..17
FT /note="mgtA leader peptide"
FT /id="PRO_0000403453"
SQ SEQUENCE 17 AA; 2123 MW; 0F46CE7376700551 CRC64;
MEPDPTPLPR RRLKLFR