ID   LPPA_MYCTO              Reviewed;         219 AA.
AC   P9WK80; L0TCP2; P95010; Q7D6Y4;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Putative lipoprotein LppA;
DE   Flags: Precursor;
GN   Name=lppA; OrderedLocusNames=MT2618;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the mycobacteriales LppA/LppB family.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK46929.1; -; Genomic_DNA.
DR   PIR; C70659; C70659.
DR   RefSeq; WP_003900846.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WK80; -.
DR   SMR; P9WK80; -.
DR   EnsemblBacteria; AAK46929; AAK46929; MT2618.
DR   KEGG; mtc:MT2618; -.
DR   PATRIC; fig|83331.31.peg.2824; -.
DR   HOGENOM; CLU_097903_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR032018; LppA/LppB/LprP.
DR   Pfam; PF16708; LppA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000255"
FT   CHAIN           33..219
FT                   /note="Putative lipoprotein LppA"
FT                   /id="PRO_0000427700"
FT   LIPID           33
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255"
FT   LIPID           33
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   219 AA;  24180 MW;  C3DCF4370051F552 CRC64;
     MIAPQPISRT LPRWQRIVAL TMIGISTALI GGCTMDHNPD TSRRLTGEQK IQLIDSMRNK
     GSYEAARERL TATARIIADR VSAAIPGQTW KFDDDPNIQQ SDRNGALCDK LTADIARRPI
     ANSVMFGATF SAEDFKIAAN IVREEAAKYG ATTESSLFNE SAKRDYDVQG NGYEFRLLQI
     KFATLNITGD CFLLQKVLDL PAGQLPPEPP IWPTTSTPH