LPPA_MYCTO
ID LPPA_MYCTO Reviewed; 219 AA.
AC P9WK80; L0TCP2; P95010; Q7D6Y4;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Putative lipoprotein LppA;
DE Flags: Precursor;
GN Name=lppA; OrderedLocusNames=MT2618;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the mycobacteriales LppA/LppB family.
CC {ECO:0000305}.
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DR EMBL; AE000516; AAK46929.1; -; Genomic_DNA.
DR PIR; C70659; C70659.
DR RefSeq; WP_003900846.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WK80; -.
DR SMR; P9WK80; -.
DR EnsemblBacteria; AAK46929; AAK46929; MT2618.
DR KEGG; mtc:MT2618; -.
DR PATRIC; fig|83331.31.peg.2824; -.
DR HOGENOM; CLU_097903_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032018; LppA/LppB/LprP.
DR Pfam; PF16708; LppA; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT SIGNAL 1..32
FT /evidence="ECO:0000255"
FT CHAIN 33..219
FT /note="Putative lipoprotein LppA"
FT /id="PRO_0000427700"
FT LIPID 33
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255"
FT LIPID 33
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 219 AA; 24180 MW; C3DCF4370051F552 CRC64;
MIAPQPISRT LPRWQRIVAL TMIGISTALI GGCTMDHNPD TSRRLTGEQK IQLIDSMRNK
GSYEAARERL TATARIIADR VSAAIPGQTW KFDDDPNIQQ SDRNGALCDK LTADIARRPI
ANSVMFGATF SAEDFKIAAN IVREEAAKYG ATTESSLFNE SAKRDYDVQG NGYEFRLLQI
KFATLNITGD CFLLQKVLDL PAGQLPPEPP IWPTTSTPH