ID   LPPB_HAEIN              Reviewed;         405 AA.
AC   P44833;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Outer membrane antigenic lipoprotein B;
DE   Flags: Precursor;
GN   Name=lppB; OrderedLocusNames=HI_0706;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: May be a virulence determinant.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC   -!- SIMILARITY: Belongs to the E.coli NlpD/Haemophilus LppB family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L42023; AAC22363.1; -; Genomic_DNA.
DR   PIR; F64087; F64087.
DR   RefSeq; NP_438864.1; NC_000907.1.
DR   RefSeq; WP_005694590.1; NC_000907.1.
DR   AlphaFoldDB; P44833; -.
DR   SMR; P44833; -.
DR   STRING; 71421.HI_0706; -.
DR   EnsemblBacteria; AAC22363; AAC22363; HI_0706.
DR   KEGG; hin:HI_0706; -.
DR   PATRIC; fig|71421.8.peg.736; -.
DR   eggNOG; COG1388; Bacteria.
DR   eggNOG; COG4942; Bacteria.
DR   HOGENOM; CLU_029425_1_1_6; -.
DR   OMA; TMFLIAY; -.
DR   PhylomeDB; P44833; -.
DR   BioCyc; HINF71421:G1GJ1-739-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR   GO; GO:0009279; C:cell outer membrane; IBA:GO_Central.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IBA:GO_Central.
DR   GO; GO:0000920; P:septum digestion after cytokinesis; IBA:GO_Central.
DR   CDD; cd00118; LysM; 1.
DR   Gene3D; 2.70.70.10; -; 1.
DR   Gene3D; 3.10.350.10; -; 1.
DR   InterPro; IPR011055; Dup_hybrid_motif.
DR   InterPro; IPR018392; LysM_dom.
DR   InterPro; IPR036779; LysM_dom_sf.
DR   InterPro; IPR016047; Peptidase_M23.
DR   Pfam; PF01476; LysM; 1.
DR   Pfam; PF01551; Peptidase_M23; 1.
DR   SMART; SM00257; LysM; 1.
DR   SUPFAM; SSF51261; SSF51261; 1.
DR   PROSITE; PS51782; LYSM; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal; Virulence.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000305"
FT   CHAIN           18..405
FT                   /note="Outer membrane antigenic lipoprotein B"
FT                   /id="PRO_0000018034"
FT   DOMAIN          145..189
FT                   /note="LysM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01118"
FT   REGION          81..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           18
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           18
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   405 AA;  42505 MW;  4134FB6B93EFE57F CRC64;
     MKKSFLLLPL SLVVLSACTS NFPAPISDAD GNFSPSVIQS VNGSNVGGAW QPEIQKNSLP
     TTGNMVTPQQ NFQPINQQPT MPTAPAQPAF QPSPKTVVSA PTVQTKTVTK TVADCVDGQH
     INIPRNPNTN APDYSKISKG SYKGNTYKVN KGDTMFLIAY LAGIDVKELA ALNNLSEPYN
     LSLGQVLKIS NCDIKTVTTT VSVKQPAVTA STATPVKPAV TYTPGANGTQ IGSDGTIIGP
     IKSEAGTSPS VPVATSSTQV TSSVNNANST PINSNVVAPI ASNVVWQWPT SGNIIQGFSS
     TDGGNKGIDI SGSRGQAVKA AAAGRIVYAG NALRGYGNLI IIKHNDDFLS AYAHNDKILV
     ADQQEVKAGQ DIAKMGSSGT NTVKLHFEIR YKGKSVDPVR YLPRH