LPPB_MYCTO
ID LPPB_MYCTO Reviewed; 220 AA.
AC P9WK78; L0TBI8; P95009; Q7D6Y3;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 03-AUG-2022, entry version 33.
DE RecName: Full=Putative lipoprotein LppB;
DE Flags: Precursor;
GN Name=lppB; OrderedLocusNames=MT2620;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the mycobacteriales LppA/LppB family.
CC {ECO:0000305}.
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DR EMBL; AE000516; AAK46931.1; -; Genomic_DNA.
DR PIR; D70659; D70659.
DR RefSeq; WP_003900848.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WK78; -.
DR SMR; P9WK78; -.
DR PRIDE; P9WK78; -.
DR EnsemblBacteria; AAK46931; AAK46931; MT2620.
DR KEGG; mtc:MT2620; -.
DR PATRIC; fig|83331.31.peg.2826; -.
DR HOGENOM; CLU_097903_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032018; LppA/LppB/LprP.
DR Pfam; PF16708; LppA; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT SIGNAL 1..32
FT /evidence="ECO:0000255"
FT CHAIN 33..220
FT /note="Putative lipoprotein LppB"
FT /id="PRO_0000427701"
FT LIPID 33
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255"
FT LIPID 33
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 220 AA; 24193 MW; 7301524BC75A9781 CRC64;
MIAPQPIPRT LPRWQRIVAL TMIGISTALI GGCTMGQNPD KSPHLTGEQK IQLIDSMRHK
GSYEAARERL TATAQIIADR VSAAIPGQTW KFNDDSYGQD FYRNGSLCKE LSADIARRPM
AKPVDFGSTF SAEDFKIAAN IVREEAAKYG VTTESSLFNE SAKRDYDVQG NGYEFNLGQI
KFATLNITGD CFLLQKVLDL PAGQLPPEPP IWPTTSTPTP