LPPB_MYCTU
ID LPPB_MYCTU Reviewed; 220 AA.
AC P9WK79; L0TBI8; P95009; Q7D6Y3;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 28.
DE RecName: Full=Putative lipoprotein LppB;
DE Flags: Precursor;
GN Name=lppB; OrderedLocusNames=Rv2544;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the mycobacteriales LppA/LppB family.
CC {ECO:0000305}.
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DR EMBL; AL123456; CCP45339.1; -; Genomic_DNA.
DR PIR; D70659; D70659.
DR RefSeq; NP_217060.1; NC_000962.3.
DR RefSeq; WP_003900848.1; NZ_NVQJ01000032.1.
DR AlphaFoldDB; P9WK79; -.
DR SMR; P9WK79; -.
DR STRING; 83332.Rv2544; -.
DR PaxDb; P9WK79; -.
DR DNASU; 888054; -.
DR GeneID; 888054; -.
DR KEGG; mtu:Rv2544; -.
DR TubercuList; Rv2544; -.
DR eggNOG; ENOG5031J3X; Bacteria.
DR OMA; YEFELMQ; -.
DR PhylomeDB; P9WK79; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0005576; C:extracellular region; HDA:MTBBASE.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032018; LppA/LppB/LprP.
DR Pfam; PF16708; LppA; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..32
FT /evidence="ECO:0000255"
FT CHAIN 33..220
FT /note="Putative lipoprotein LppB"
FT /id="PRO_0000361671"
FT LIPID 33
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255"
FT LIPID 33
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 220 AA; 24193 MW; 7301524BC75A9781 CRC64;
MIAPQPIPRT LPRWQRIVAL TMIGISTALI GGCTMGQNPD KSPHLTGEQK IQLIDSMRHK
GSYEAARERL TATAQIIADR VSAAIPGQTW KFNDDSYGQD FYRNGSLCKE LSADIARRPM
AKPVDFGSTF SAEDFKIAAN IVREEAAKYG VTTESSLFNE SAKRDYDVQG NGYEFNLGQI
KFATLNITGD CFLLQKVLDL PAGQLPPEPP IWPTTSTPTP