ID   LPPC_MYCBO              Reviewed;         201 AA.
AC   P67225; A0A1R3XZR4; O07722; X2BJB0;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-NOV-2015, sequence version 2.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Putative lipoprotein LppC;
DE   AltName: Full=UPF0098 protein Mb1946c;
DE   Flags: Precursor;
GN   Name=lppC; OrderedLocusNames=BQ2027_MB1946C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the UPF0098 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT708304; SIU00549.1; -; Genomic_DNA.
DR   RefSeq; NP_855597.1; NC_002945.3.
DR   RefSeq; WP_003409568.1; NC_002945.4.
DR   AlphaFoldDB; P67225; -.
DR   SMR; P67225; -.
DR   EnsemblBacteria; SIU00549; SIU00549; BQ2027_MB1946C.
DR   PATRIC; fig|233413.5.peg.2135; -.
DR   OMA; CWVVVNI; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd00865; PEBP_bact_arch; 1.
DR   Gene3D; 3.90.280.10; -; 1.
DR   InterPro; IPR008914; PEBP.
DR   InterPro; IPR036610; PEBP-like_sf.
DR   InterPro; IPR005247; YbhB_YbcL.
DR   PANTHER; PTHR30289; PTHR30289; 1.
DR   Pfam; PF01161; PBP; 1.
DR   SUPFAM; SSF49777; SSF49777; 1.
DR   TIGRFAMs; TIGR00481; TIGR00481; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           24..201
FT                   /note="Putative lipoprotein LppC"
FT                   /id="PRO_0000137908"
FT   REGION          122..141
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..136
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           24
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           24
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   201 AA;  19798 MW;  42977DA20934782B CRC64;
     MTSTLHRTPL ATAGLALVVA LGGCGGGGGD SRETPPYVPK ATTVDATTPA PAAEPLTIAS
     PMFADGAPIP VQFSCKGANV APPLTWSSPA GAAELALVVD DPDAVGGLYV HWIVTGIAPG
     SGSTADGQTP AGGHSVPNSG GRQGYFGPCP PAGTGTHHYR FTLYHLPVAL QLPPGATGVQ
     AAQAIAQAAS GQARLVGTFE G