ID   LPPC_MYCTO              Reviewed;         205 AA.
AC   P9WFN2; L0T886; O07722; P67224;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Putative lipoprotein LppC;
DE   AltName: Full=UPF0098 protein MT1962;
DE   Flags: Precursor;
GN   Name=lppC; OrderedLocusNames=MT1962;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the UPF0098 family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46234.1; -; Genomic_DNA.
DR   PIR; D70519; D70519.
DR   AlphaFoldDB; P9WFN2; -.
DR   SMR; P9WFN2; -.
DR   EnsemblBacteria; AAK46234; AAK46234; MT1962.
DR   KEGG; mtc:MT1962; -.
DR   HOGENOM; CLU_083918_3_2_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd00865; PEBP_bact_arch; 1.
DR   Gene3D; 3.90.280.10; -; 1.
DR   InterPro; IPR008914; PEBP.
DR   InterPro; IPR036610; PEBP-like_sf.
DR   InterPro; IPR005247; YbhB_YbcL.
DR   PANTHER; PTHR30289; PTHR30289; 1.
DR   Pfam; PF01161; PBP; 1.
DR   SUPFAM; SSF49777; SSF49777; 1.
DR   TIGRFAMs; TIGR00481; TIGR00481; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           28..205
FT                   /note="Putative lipoprotein LppC"
FT                   /id="PRO_0000428509"
FT   REGION          126..145
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..140
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           28
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           28
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   205 AA;  20243 MW;  6962B69277A2DC3D CRC64;
     MESPMTSTLH RTPLATAGLA LVVALGGCGG GGGDSRETPP YVPKATTVDA TTPAPAAEPL
     TIASPMFADG APIPVQFSCK GANVAPPLTW SSPAGAAELA LVVDDPDAVG GLYVHWIVTG
     IAPGSGSTAD GQTPAGGHSV PNSGGRQGYF GPCPPAGTGT HHYRFTLYHL PVALQLPPGA
     TGVQAAQAIA QAASGQARLV GTFEG