LPPJ_MYCTU
ID LPPJ_MYCTU Reviewed; 187 AA.
AC P9WK77; L0TBA5; Q10688;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Putative lipoprotein LppJ;
DE Flags: Precursor;
GN Name=lppJ; OrderedLocusNames=Rv2080; ORFNames=MTCY49.19;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
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DR EMBL; AL123456; CCP44855.1; -; Genomic_DNA.
DR PIR; C70766; C70766.
DR RefSeq; NP_216596.1; NC_000962.3.
DR RefSeq; WP_003899161.1; NZ_NVQJ01000047.1.
DR AlphaFoldDB; P9WK77; -.
DR STRING; 83332.Rv2080; -.
DR PaxDb; P9WK77; -.
DR DNASU; 887351; -.
DR GeneID; 887351; -.
DR KEGG; mtu:Rv2080; -.
DR TubercuList; Rv2080; -.
DR eggNOG; ENOG50305SF; Bacteria.
DR OMA; RVEVAFK; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0005576; C:extracellular region; HDA:MTBBASE.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..187
FT /note="Putative lipoprotein LppJ"
FT /id="PRO_0000018108"
FT LIPID 29
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 29
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 187 AA; 20324 MW; 0A8851161BA5A668 CRC64;
MPHSTADRRL RLTRQALLAA AVVPLLAGCA LVMHKPHSAG SSNPWDDSAH PLTDDQAMAQ
VVEPAKQIVA AADLQAVRAG FSFTSCNDQG DPPYQGTVRM AFLLQGDHDA YFQHVRAAML
SHGWIDGPPP GQYFHGITLH KNGVTANMSL ALDHSYGEMI LDGECRNTTD HHHDDETTNI
TNQLVQP