ID   LPPK_MYCLE              Reviewed;         194 AA.
AC   Q49803;
DT   05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Putative lipoprotein LppK;
DE   Flags: Precursor;
GN   Name=lppK; OrderedLocusNames=ML1315; ORFNames=B2126_F3_115, MLCB2533.11c;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Smith D.R., Robison K.;
RL   Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the MTB12 family. {ECO:0000305}.
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DR   EMBL; U00017; AAA17217.1; -; Genomic_DNA.
DR   EMBL; AL035310; CAA22925.1; -; Genomic_DNA.
DR   EMBL; AL583921; CAC31696.1; -; Genomic_DNA.
DR   PIR; S72877; S72877.
DR   RefSeq; NP_301946.1; NC_002677.1.
DR   RefSeq; WP_010908267.1; NC_002677.1.
DR   AlphaFoldDB; Q49803; -.
DR   STRING; 272631.ML1315; -.
DR   EnsemblBacteria; CAC31696; CAC31696; CAC31696.
DR   KEGG; mle:ML1315; -.
DR   PATRIC; fig|272631.5.peg.2426; -.
DR   Leproma; ML1315; -.
DR   eggNOG; ENOG5030NVW; Bacteria.
DR   HOGENOM; CLU_084151_2_0_11; -.
DR   OMA; TFPMEFT; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           27..194
FT                   /note="Putative lipoprotein LppK"
FT                   /id="PRO_0000018110"
FT   REGION          174..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           27
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           27
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   194 AA;  20460 MW;  E975262FC3218A86 CRC64;
     MSRWTHRTFF IALSAIVTTA GFGSSGCAHG NSSTSESAVP STFPGISSSI TAPPATGLPA
     PEVLTNVLSR LADPNIPGID KLPLIESATP DSAVTLDKFS NALRDNGYLP MTFTANNIAW
     SNKNPSDVLA TISVNIAQTN NSVFSFPMEF TPFPPPQQSW QLSKRTADML LEFGNSSGLT
     NPAPIKAPTP TPSH