ID   LPPK_MYCTO              Reviewed;         189 AA.
AC   P9WK74; L0TBK6; O33251; P65300;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Putative lipoprotein LppK;
DE   Flags: Precursor;
GN   Name=lppK; OrderedLocusNames=MT2176;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the MTB12 family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46459.1; -; Genomic_DNA.
DR   PIR; G70512; G70512.
DR   RefSeq; WP_003900470.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WK74; -.
DR   EnsemblBacteria; AAK46459; AAK46459; MT2176.
DR   KEGG; mtc:MT2176; -.
DR   PATRIC; fig|83331.31.peg.2346; -.
DR   HOGENOM; CLU_084151_2_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..189
FT                   /note="Putative lipoprotein LppK"
FT                   /id="PRO_0000427703"
FT   REGION          26..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          166..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   189 AA;  19728 MW;  FBF63A33BF83CB77 CRC64;
     MRRNIRVTLG AATIVAALGL SGCSHPEFKR SSPPAPSLPP VTSSPLEAAP ITPLPAPEAL
     IDVLSRLADP AVPGTNKVQL IEGATPENAA ALDRFTTALR DGSYLPMTFA ANDIAWSDNK
     PSDVMATVVV TTAHPDNREF TFPMEFVSFK GGWQLSRQTA EMLLAMGNSP DSTPSATSPA
     PAPSPTPPG