LPPW_MYCBO
ID LPPW_MYCBO Reviewed; 314 AA.
AC P65305; A0A1R3Y2J3; Q10823; X2BMR5;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Putative lipoprotein LppW;
DE Flags: Precursor;
GN Name=lppW; OrderedLocusNames=BQ2027_MB2929;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
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DR EMBL; LT708304; SIU01550.1; -; Genomic_DNA.
DR RefSeq; NP_856574.1; NC_002945.3.
DR RefSeq; WP_003414720.1; NC_002945.4.
DR AlphaFoldDB; P65305; -.
DR SMR; P65305; -.
DR EnsemblBacteria; SIU01550; SIU01550; BQ2027_MB2929.
DR GeneID; 45426892; -.
DR PATRIC; fig|233413.5.peg.3215; -.
DR OMA; GRWFNTI; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.710.10; -; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR SUPFAM; SSF56601; SSF56601; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 23..314
FT /note="Putative lipoprotein LppW"
FT /id="PRO_0000018117"
FT LIPID 23
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 23
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 314 AA; 33402 MW; DE963F5F4C55154D CRC64;
MRARPLTLLT ALAAVTLVVV AGCEARVEAE AYSAADRISS RPQARPQPQP VELLLRAITP
PRAPAASPNV GFGELPTRVR QATDEAAAMG ATLSVAVLDR ATGQLVSNGN TQIIATASVA
KLFIADDLLL AEAEGKVTLS PEDHHALDVM LQSSDDGAAE RFWSQDGGNA VVTQVARRYG
LRSTAPPSDG RWWNTISSAP DLIRYYDMLL DGSGGLPLDR AAVIIADLAQ STPTGIDGYP
QRFGIPDGLY AEPVAVKQGW MCCIGSSWMH LSTGVIGPER RYIMVIESLQ PADDATARAT
ITQAVRTMFP NGRI