ID   LPPW_MYCTO              Reviewed;         314 AA.
AC   P9WK66; L0TDW9; P65304; Q10823;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Putative lipoprotein LppW;
DE   Flags: Precursor;
GN   Name=lppW; OrderedLocusNames=MT2973;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
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DR   EMBL; AE000516; AAK47299.1; -; Genomic_DNA.
DR   PIR; D70927; D70927.
DR   RefSeq; WP_003414720.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WK66; -.
DR   SMR; P9WK66; -.
DR   EnsemblBacteria; AAK47299; AAK47299; MT2973.
DR   GeneID; 45426892; -.
DR   KEGG; mtc:MT2973; -.
DR   PATRIC; fig|83331.31.peg.3213; -.
DR   HOGENOM; CLU_061997_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.710.10; -; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   SUPFAM; SSF56601; SSF56601; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..314
FT                   /note="Putative lipoprotein LppW"
FT                   /id="PRO_0000427707"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   314 AA;  33402 MW;  DE963F5F4C55154D CRC64;
     MRARPLTLLT ALAAVTLVVV AGCEARVEAE AYSAADRISS RPQARPQPQP VELLLRAITP
     PRAPAASPNV GFGELPTRVR QATDEAAAMG ATLSVAVLDR ATGQLVSNGN TQIIATASVA
     KLFIADDLLL AEAEGKVTLS PEDHHALDVM LQSSDDGAAE RFWSQDGGNA VVTQVARRYG
     LRSTAPPSDG RWWNTISSAP DLIRYYDMLL DGSGGLPLDR AAVIIADLAQ STPTGIDGYP
     QRFGIPDGLY AEPVAVKQGW MCCIGSSWMH LSTGVIGPER RYIMVIESLQ PADDATARAT
     ITQAVRTMFP NGRI