LPP_MYCMS
ID LPP_MYCMS Reviewed; 548 AA.
AC P55802;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2004, sequence version 2.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Uncharacterized lipoprotein lpp;
DE Flags: Precursor;
GN Name=lpp; OrderedLocusNames=MSC_0013;
OS Mycoplasma mycoides subsp. mycoides SC (strain PG1).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=272632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PG1;
RX PubMed=14762060; DOI=10.1101/gr.1673304;
RA Westberg J., Persson A., Holmberg A., Goesmann A., Lundeberg J.,
RA Johansson K.-E., Pettersson B., Uhlen M.;
RT "The genome sequence of Mycoplasma mycoides subsp. mycoides SC type strain
RT PG1T, the causative agent of contagious bovine pleuropneumonia (CBPP).";
RL Genome Res. 14:221-227(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 136-548.
RC STRAIN=L2;
RX PubMed=9004514; DOI=10.1099/13500872-142-12-3515;
RA Cheng X., Nicolet J., Miserez R., Kuhnert P., Krampe M., Pilloud T.,
RA Abdo E.-M., Griot C., Frey J.;
RT "Characterization of the gene for an immunodominant 72 kDa lipoprotein of
RT Mycoplasma mycoides subsp. mycoides small colony type.";
RL Microbiology 142:3515-3524(1996).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the mycoplasma p72 lipoprotein family.
CC {ECO:0000305}.
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DR EMBL; BX293980; CAE76666.1; -; Genomic_DNA.
DR EMBL; U61140; AAC44570.1; -; Genomic_DNA.
DR RefSeq; NP_975024.1; NC_005364.2.
DR AlphaFoldDB; P55802; -.
DR STRING; 272632.MSC_0013; -.
DR PRIDE; P55802; -.
DR EnsemblBacteria; CAE76666; CAE76666; MSC_0013.
DR KEGG; mmy:MSC_0013; -.
DR PATRIC; fig|272632.4.peg.13; -.
DR eggNOG; ENOG5032EJB; Bacteria.
DR HOGENOM; CLU_030565_0_0_14; -.
DR OMA; TNPANDM; -.
DR Proteomes; UP000001016; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR019992; Mycoides_lipoprot_LppA/p72.
DR TIGRFAMs; TIGR03490; Mycoplas_LppA; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 25..548
FT /note="Uncharacterized lipoprotein lpp"
FT /id="PRO_0000018098"
FT REGION 26..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 25
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 25
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 548 AA; 62619 MW; 784969B2258376AC CRC64;
MKKATKLLLS ILPISSISFL SVVSCSTRNS NAKQPDKKPE KPNEKGPIIP KNPDNKKPTN
NNNNSNNNSN SNNNKPGSTV PNENKDPSKS EETPEKPERD PKKPDKQPQG DDPNNHQPHN
NQHADQPNIN KDEFADLDKL PKEISFERFD FYTSKDATTA LSHLRTDGSV IKIIFSNTHR
NIFGKYNINL ELDGNEKEDV KKGLIDKVKV KFTNKKDKKS KIIEFTFTGF KVIQKSPDKE
NKNSKKNYIK KKEKIDNKLT GLYPSLVAYM IMYTQEPKNY KNLMQKDSIN FEELENNNPN
LFADPEINLN VVALKDLLLE YNRELGKLYK DKVIAVSYDD VNGKLGLKLL IENREENDTI
ASKYSETLEF DFVGFRKIDL KNPNKNVLSL LFPQNNFKDM IKNNVFKKKI EVLKSGKQKE
DMVLVKEEYA KQLIFKNLLV QIIDNENNLY RSTQTLSLQN NKKDNYTSIL GLAGGGTLYP
FHTIINNNSI KNIYLMINKE KNKKYKVAIN FEVDIPIFAS TTSDLTFHAT SGDTNILKLD
ITTNALID
