ID   LPQB_MYCTO              Reviewed;         587 AA.
AC   P9WK36; L0TC87; O05889; Q7D5U9;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Lipoprotein LpqB {ECO:0000255|HAMAP-Rule:MF_01373};
DE   Flags: Precursor;
GN   Name=lpqB {ECO:0000255|HAMAP-Rule:MF_01373}; OrderedLocusNames=MT3342;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: May modulate activity of the MtrAB system in controlling
CC       homeostasis of the cell wall and cell division. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with MtrB, probably extracytoplasmically.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01373};
CC       Lipid-anchor {ECO:0000255|HAMAP-Rule:MF_01373}. Secreted, cell wall
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LpqB lipoprotein family. {ECO:0000255|HAMAP-
CC       Rule:MF_01373}.
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DR   EMBL; AE000516; AAK47684.1; -; Genomic_DNA.
DR   PIR; F70592; F70592.
DR   AlphaFoldDB; P9WK36; -.
DR   SMR; P9WK36; -.
DR   EnsemblBacteria; AAK47684; AAK47684; MT3342.
DR   KEGG; mtc:MT3342; -.
DR   HOGENOM; CLU_032207_1_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01373; LpqB_lipoprot; 1.
DR   InterPro; IPR019606; GerMN.
DR   InterPro; IPR023959; Lipoprotein_LpqB.
DR   InterPro; IPR018910; Lipoprotein_LpqB_C.
DR   Pfam; PF10646; Germane; 1.
DR   Pfam; PF10647; Gmad1; 1.
DR   SMART; SM00909; Germane; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cell wall; Lipoprotein; Membrane; Palmitate; Secreted;
KW   Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01373"
FT   CHAIN           20..587
FT                   /note="Lipoprotein LpqB"
FT                   /id="PRO_0000427722"
FT   LIPID           20
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01373"
FT   LIPID           20
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01373"
SQ   SEQUENCE   587 AA;  61681 MW;  1E2C7D25A2C5D91B CRC64;
     MERLMRLTIL LFLGAVLAGC ASVPSTSAPQ AIGTVERPVP SNLPKPSPGM DPDVLLREFL
     KATADPANRH LAARQFLTES ASNAWDDAGS ALLIDHVVFV ETRSAEKVSV TMRADILGSL
     SDVGVFETAE GQLPDPGPIE LVKTSDGWRI DRLPNGVFLD WQQFQETYKR NTLYFADPTG
     KTVVPDPRYV AVSDRDQLAT ELVSKLLAGP RPEMARTVRN LLAPPLRLRG PVTRADGGKS
     GIGRGYGGAR VDMEKLSTTD PHSRQLLAAQ IIWTLARADI RGPYVINADG APLEDRFAEG
     WTTSDVAATD PGVADGAAAG LHALVNGSLV AMDAQRVTPV PGAFGRMPEQ TAAAVSRSGR
     QVASVVTLGR GAPDEAASLW VGDLGGEAVQ SADGHSLSRP SWSLDDAVWV VVDTNVVLRA
     IQDPASGQPA RIPVDSTAVA SRFPGAINDL QLSRDGTRAA MVIGGQVILA GVEQTQAGQF
     ALTYPRRLGF GLGSSVVSLS WRTGDDIVVT RTDAAHPVSY VNLDGVNSDA PSRGLQTPLT
     AIAANPSTVY VAGPQGVLMY SASVESRPGW ADVPGLMVPG AAPVLPG