ID   LPRB_MYCTO              Reviewed;         185 AA.
AC   P9WK52; L0T7T1; Q11045;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Putative lipoprotein LprB;
DE   Flags: Precursor;
GN   Name=lprB; OrderedLocusNames=MT1312;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK45572.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000516; AAK45572.1; ALT_INIT; Genomic_DNA.
DR   PIR; B70755; B70755.
DR   RefSeq; WP_003901123.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WK52; -.
DR   EnsemblBacteria; AAK45572; AAK45572; MT1312.
DR   KEGG; mtc:MT1312; -.
DR   PATRIC; fig|83331.31.peg.1417; -.
DR   HOGENOM; CLU_129265_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR024520; DUF3558.
DR   Pfam; PF12079; DUF3558; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           25..185
FT                   /note="Putative lipoprotein LprB"
FT                   /id="PRO_0000427714"
FT   REGION          26..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           25
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           25
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   185 AA;  19739 MW;  B412D6C748229453 CRC64;
     MRRKVRRLTL AVSALVALFP AVAGCSDSGD NKPGATIPST PANAEGRHGP FFPQCGGVSD
     QTVTELTRVT GLVNTAKNSV GCQWLAGGGI LGPHFSFSWY RGSPIGRERK TEELSRASVE
     DINIDGHSGF IAIGNEPSLG DSLCEVGIQF SDDFIEWSVS FSQKPFPLPC DIAKELTRQS
     IANSK