ID   LPRD_MYCLE              Reviewed;         126 AA.
AC   P54134;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Putative lipoprotein LprD;
DE   Flags: Precursor;
GN   Name=lprD; OrderedLocusNames=ML1177; ORFNames=B1549_F3_106, MLCB1701.03c;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Smith D.R., Robison K.;
RL   Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC       Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Single-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.tuberculosis Rv1343c. {ECO:0000305}.
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DR   EMBL; U00014; AAA50903.1; -; Genomic_DNA.
DR   EMBL; AL049191; CAB39143.1; -; Genomic_DNA.
DR   EMBL; AL583921; CAC31558.1; -; Genomic_DNA.
DR   PIR; S72785; S72785.
DR   RefSeq; NP_301859.1; NC_002677.1.
DR   RefSeq; WP_010908183.1; NC_002677.1.
DR   AlphaFoldDB; P54134; -.
DR   STRING; 272631.ML1177; -.
DR   EnsemblBacteria; CAC31558; CAC31558; CAC31558.
DR   KEGG; mle:ML1177; -.
DR   PATRIC; fig|272631.5.peg.2134; -.
DR   Leproma; ML1177; -.
DR   eggNOG; COG1566; Bacteria.
DR   HOGENOM; CLU_122754_0_0_11; -.
DR   OMA; WQWTRFE; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           20..126
FT                   /note="Putative lipoprotein LprD"
FT                   /id="PRO_0000103818"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   LIPID           20
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           20
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   126 AA;  14480 MW;  6B7096956561908D CRC64;
     MSTTRRRRPA LVALVTIAAC GCLALGWWQW TRFQSASGTF QNLGYALQWP LFAGFCLYTY
     HNFVRYEESP PQPRHMNCIA EIPPELLPAR PKPEQQPPDD PALRKYNTYL AELAKQDAEN
     HNRTTT