ID   LPRD_MYCTO              Reviewed;         126 AA.
AC   P9WK50; L0T6D1; Q11013;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Putative lipoprotein LprD;
DE   Flags: Precursor;
GN   Name=lprD; OrderedLocusNames=MT1384;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC       Cell membrane {ECO:0000255|PROSITE-ProRule:PRU00303}; Single-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.leprae ML1177. {ECO:0000305}.
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DR   EMBL; AE000516; AAK45649.1; -; Genomic_DNA.
DR   PIR; F70739; F70739.
DR   RefSeq; WP_003898833.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WK50; -.
DR   SMR; P9WK50; -.
DR   EnsemblBacteria; AAK45649; AAK45649; MT1384.
DR   KEGG; mtc:MT1384; -.
DR   PATRIC; fig|83331.31.peg.1492; -.
DR   HOGENOM; CLU_122754_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           22..126
FT                   /note="Putative lipoprotein LprD"
FT                   /id="PRO_0000427715"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          70..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           22
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           22
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   126 AA;  14273 MW;  EFE23311D1FDC205 CRC64;
     MSTTRRRRPA LIALVIIATC GCLALGWWQW TRFQSTSGTF QNLGYALQWP LFAWFCVYAY
     RNFVRYEETP PQPPTGGAAA EIPAGLLPER PKPAQQPPDD PVLREYNAYL AELAKDDARK
     QNRTTA