LPRE_MYCBO
ID LPRE_MYCBO Reviewed; 202 AA.
AC P65313; A0A1R3XY46; Q11065; X2BHG1;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Putative lipoprotein LprE;
DE Flags: Precursor;
GN Name=lprE; OrderedLocusNames=BQ2027_MB1284C;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
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DR EMBL; LT708304; SIT99885.1; -; Genomic_DNA.
DR RefSeq; NP_854938.1; NC_002945.3.
DR RefSeq; WP_003406334.1; NC_002945.4.
DR AlphaFoldDB; P65313; -.
DR EnsemblBacteria; SIT99885; SIT99885; BQ2027_MB1284C.
DR PATRIC; fig|233413.5.peg.1407; -.
DR OMA; PRSQQPW; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR025971; LppP/LprE.
DR Pfam; PF14041; Lipoprotein_21; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..202
FT /note="Putative lipoprotein LprE"
FT /id="PRO_0000018139"
FT REGION 29..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 51..65
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 29
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255"
FT LIPID 29
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 202 AA; 20442 MW; E3DCE415A91DAAFE CRC64;
MPGVWSPPCP TTPRVGVVAA LVAATLTGCG SGDSTVAKTP EATPSLSTAH PAPPSSEPSP
PSATAAPPSN HSAAPVDPCA VNLASPTIAK VVSELPRDPR SEQPWNPEPL AGNYNECAQL
SAVVIKANTN AGNPTTRAVM FHLGKYIPQG VPDTYGFTGI DTSQCTGDTV ALTYASGIGL
NNVVKFRWNG GGVELIGNTT GG