ID   LPRH_ECOLI              Reviewed;          33 AA.
AC   P0ADF3; A0A385XJP7; P37324; Q2M890;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=rho operon leader peptide;
DE            Short=RhoL;
GN   Name=rhoL; OrderedLocusNames=b3782, JW3755;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND POSSIBLE FUNCTION.
RC   STRAIN=K12;
RX   PubMed=6219230; DOI=10.1016/0022-2836(82)90527-7;
RA   Brown S., Albrechtsen B., Pedersen S., Klemm P.;
RT   "Localization and regulation of the structural gene for transcription-
RT   termination factor rho of Escherichia coli.";
RL   J. Mol. Biol. 162:283-298(1982).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=6304634; DOI=10.1093/nar/11.11.3531;
RA   Pinkham J.L., Platt T.;
RT   "The nucleotide sequence of the rho gene of E. coli K-12.";
RL   Nucleic Acids Res. 11:3531-3545(1983).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6099324; DOI=10.1016/0378-1119(84)90015-5;
RA   Wallace B.J., Kushner S.R.;
RT   "Genetic and physical analysis of the thioredoxin (trxA) gene of
RT   Escherichia coli K-12.";
RL   Gene 32:399-408(1984).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=1379743; DOI=10.1126/science.1379743;
RA   Daniels D.L., Plunkett G. III, Burland V.D., Blattner F.R.;
RT   "Analysis of the Escherichia coli genome: DNA sequence of the region from
RT   84.5 to 86.5 minutes.";
RL   Science 257:771-778(1992).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [7]
RP   POSSIBLE FUNCTION.
RX   PubMed=2423505; DOI=10.1128/jb.166.3.945-958.1986;
RA   Matsumoto Y., Shigesada K., Hirano M., Imai M.;
RT   "Autogenous regulation of the gene for transcription termination factor rho
RT   in Escherichia coli: localization and function of its attenuators.";
RL   J. Bacteriol. 166:945-958(1986).
CC   -!- FUNCTION: The rhoL-rho operon is regulated via attenuation by Rho-
CC       dependent terminators within the sequence coding for the RhoL leader
CC       peptide. It has not been determined if translation of rhoL is required
CC       for this Rho-dependent termination to function.
CC       {ECO:0000305|PubMed:2423505, ECO:0000305|PubMed:6219230}.
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DR   EMBL; J01673; AAA24531.1; -; Genomic_DNA.
DR   EMBL; K02845; AAA24535.1; -; Genomic_DNA.
DR   EMBL; M87049; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U00096; AYC08255.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77516.1; -; Genomic_DNA.
DR   PIR; A05111; A05111.
DR   RefSeq; WP_001295255.1; NZ_STEB01000021.1.
DR   AlphaFoldDB; P0ADF3; -.
DR   IntAct; P0ADF3; 1.
DR   STRING; 316407.85676266; -.
DR   PRIDE; P0ADF3; -.
DR   EnsemblBacteria; AYC08255; AYC08255; b3782.
DR   EnsemblBacteria; BAE77516; BAE77516; BAE77516.
DR   GeneID; 66672315; -.
DR   KEGG; ecj:JW3755; -.
DR   EchoBASE; EB4306; -.
DR   HOGENOM; CLU_3381617_0_0_6; -.
DR   BioCyc; EcoCyc:EG12428-MON; -.
DR   PRO; PR:P0ADF3; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0031555; P:transcriptional attenuation; IMP:EcoCyc.
PE   4: Predicted;
KW   Leader peptide; Reference proteome.
FT   PEPTIDE         1..33
FT                   /note="rho operon leader peptide"
FT                   /id="PRO_0000045078"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   33 AA;  3750 MW;  8CC2DC4B6C03B589 CRC64;
     MRSEQISGSS LNPSCRFSSA YSPVTRQRKD MSR