ID   LPRH_MYCBO              Reviewed;         228 AA.
AC   P65317; A0A1R3XYP4; P71687; X2BHV9;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Putative lipoprotein LprH;
DE   Flags: Precursor;
GN   Name=lprH; OrderedLocusNames=BQ2027_MB1453;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
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DR   EMBL; LT708304; SIU00056.1; -; Genomic_DNA.
DR   RefSeq; NP_855105.1; NC_002945.3.
DR   RefSeq; WP_003407343.1; NC_002945.4.
DR   AlphaFoldDB; P65317; -.
DR   EnsemblBacteria; SIU00056; SIU00056; BQ2027_MB1453.
DR   PATRIC; fig|233413.5.peg.1588; -.
DR   OMA; TAMYAES; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           28..228
FT                   /note="Putative lipoprotein LprH"
FT                   /id="PRO_0000018147"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   LIPID           28
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           28
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   228 AA;  24288 MW;  3C069DD0EB00498A CRC64;
     MACLGRPGCR GWAGASLVLV VVLALAACTE SVAGRAMRAT DRSSGLPTSA KPARARDLLL
     QDGDRAPFGQ VTQSRVGDSY FTSAVPPECS AALLFKGSPL RPDGSSDHAE AAYNVTGPLP
     YAESVDVYTN VLNVHDVVWN GFRDVSHCRG DAVGVSRAGR STPMRLRYFA TLSDGVLVWT
     MSNPRWTCDY GLAVVPHAVL VLSACGFKPG FPMAEWASKR RAQLDSQV