ID   LPRM_ECOLX              Reviewed;          31 AA.
AC   P10739;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=23S rRNA methylase leader peptide;
DE   AltName: Full=Erythromycin resistance leader peptide;
GN   Name=ermC;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2832378; DOI=10.1128/jb.170.4.1739-1745.1988;
RA   Brisson-Noel A., Arthur M., Courvalin P.;
RT   "Evidence for natural gene transfer from Gram-positive cocci to Escherichia
RT   coli.";
RL   J. Bacteriol. 170:1739-1745(1988).
CC   -!- FUNCTION: This peptide is involved in the control mechanism of the
CC       synthesis of the erythromycin resistance protein.
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DR   EMBL; M19270; AAA25633.1; -; Genomic_DNA.
DR   PIR; A27739; A27739.
DR   RefSeq; WP_013362819.1; NZ_WTVD01000251.1.
DR   AlphaFoldDB; P10739; -.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   InterPro; IPR009391; ErmCL.
DR   Pfam; PF06308; ErmC; 1.
PE   4: Predicted;
KW   Antibiotic resistance; Leader peptide.
FT   PEPTIDE         1..31
FT                   /note="23S rRNA methylase leader peptide"
FT                   /id="PRO_0000044766"
SQ   SEQUENCE   31 AA;  3803 MW;  A2F49CEC31237110 CRC64;
     MLVFQMRYQM RYVDKTSTVL KQTKKSDYAD K