LPRP_MYCTO
ID LPRP_MYCTO Reviewed; 224 AA.
AC P9WK38; L0T5F3; P71548;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 29.
DE RecName: Full=Uncharacterized lipoprotein LprP;
DE Flags: Precursor;
GN Name=lprP; OrderedLocusNames=MT0990;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: To M.bovis LprP. {ECO:0000305}.
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DR EMBL; AE000516; AAK45238.1; -; Genomic_DNA.
DR PIR; H70717; H70717.
DR RefSeq; WP_003898662.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WK38; -.
DR EnsemblBacteria; AAK45238; AAK45238; MT0990.
DR KEGG; mtc:MT0990; -.
DR PATRIC; fig|83331.31.peg.1062; -.
DR HOGENOM; CLU_091332_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032018; LppA/LppB/LprP.
DR Pfam; PF16708; LppA; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 22..224
FT /note="Uncharacterized lipoprotein LprP"
FT /id="PRO_0000427721"
FT LIPID 22
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 22
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 224 AA; 24415 MW; 608373B8B8A402FB CRC64;
MKRTSRSLTA ALLGIAALLA GCIKPNTFDP YANPGRGELD RRQKIVNGRP DLETVQQQLA
NLDATIRAMI AKYSPQTRFS TGVTVSHLTN GCNDPFTRTI GRQEASELFF GRPAPTPQQW
LQIVTELAPV FKAAGFRPNN SVPGDPPQPL GAPNYSQIRD DGVTINLVNG DNRGPLGYSY
NTGCHLPAAW RTAPPPLNMR PANDPDVHYP YLYGSPGGRT RDAY