ID   LPSA_MANHA              Reviewed;         263 AA.
AC   Q05770;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Lipooligosaccharide biosynthesis protein LpsA;
DE            EC=2.-.-.-;
GN   Name=lpsA;
OS   Mannheimia haemolytica (Pasteurella haemolytica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Mannheimia.
OX   NCBI_TaxID=75985;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Serotype A1;
RX   PubMed=7781993; DOI=10.1111/j.1574-6968.1995.tb07560.x;
RA   Potter M.D., Lo R.Y.C.;
RT   "Cloning and characterization of a gene from Pasteurella haemolytica A1
RT   involved in lipopolysaccharide biosynthesis.";
RL   FEMS Microbiol. Lett. 129:75-81(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 189-263.
RC   STRAIN=Serotype A1;
RX   PubMed=1885539; DOI=10.1128/jb.173.18.5597-5603.1991;
RA   Abdullah K.M., Lo R.Y.C., Mellors A.;
RT   "Cloning, nucleotide sequence, and expression of the Pasteurella
RT   haemolytica A1 glycoprotease gene.";
RL   J. Bacteriol. 173:5597-5603(1991).
CC   -!- FUNCTION: Involved in the biosynthesis of a moiety on the core of the
CC       lipopolysaccharide molecule.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Note=Assembles at the inner surface of
CC       the cytoplasmic membrane. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 25 family.
CC       {ECO:0000305}.
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DR   EMBL; U15958; AAA80283.1; -; Genomic_DNA.
DR   RefSeq; WP_006249245.1; NZ_VAIO01000011.1.
DR   AlphaFoldDB; Q05770; -.
DR   STRING; 75985.WC39_09840; -.
DR   CAZy; GT25; Glycosyltransferase Family 25.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd06532; Glyco_transf_25; 1.
DR   InterPro; IPR002654; Glyco_trans_25.
DR   Pfam; PF01755; Glyco_transf_25; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Glycosyltransferase; Lipopolysaccharide biosynthesis;
KW   Transferase.
FT   CHAIN           1..263
FT                   /note="Lipooligosaccharide biosynthesis protein LpsA"
FT                   /id="PRO_0000216240"
SQ   SEQUENCE   263 AA;  30872 MW;  B07C39EC1DA603A7 CRC64;
     MNNYVISLTS AQERRKHIEA EFGKQNIPFQ FFDAITPDLI KEKAKAFNID ISNTNLTKGE
     IACALSHIAL WHLAKQQNLD YICIFEDDIY LGNNAFELLK TNYIPENTHI VKLETLPFDR
     INRFNKTEKY ILNRRLFKLN SRHVGTAGYI LTNKGAEFLI NILKTLNIPI DDLIFDEYLK
     IKEYKVLQMS PALCVQDFIL NSKTNFKSSL QDDRAIRCNN EDKIKNQAKL KKPNYFLTKI
     QKELYRPFKQ LKQKVFTTYI TFK