ID   LPSB_RHIME              Reviewed;         351 AA.
AC   Q9R9N2;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Lipopolysaccharide core biosynthesis mannosyltransferase LpsB;
DE            EC=2.4.-.-;
GN   Name=lpsB; OrderedLocusNames=R01572; ORFNames=SMc01219;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=RCR2011 / SU47;
RX   PubMed=11157937; DOI=10.1128/jb.183.4.1248-1258.2001;
RA   Lagares A., Hozbor D.F., Niehaus K., Pich Otero A.J.L., Lorenzen J.,
RA   Arnold W., Puehler A.;
RT   "Genetic characterization of a Sinorhizobium meliloti chromosomal region
RT   involved in lipopolysaccharide biosynthesis.";
RL   J. Bacteriol. 183:1248-1258(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Acts at transfer of mannose group to a 3-deoxy-D-mono
CC       octulonic acid (KDO) via an alpha-1,5 linkage. {ECO:0000250}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS core biosynthesis.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC       Glycosyltransferase 4 subfamily. {ECO:0000305}.
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DR   EMBL; AF193023; AAF06008.1; -; Genomic_DNA.
DR   EMBL; AL591688; CAC46151.1; -; Genomic_DNA.
DR   RefSeq; NP_385678.1; NC_003047.1.
DR   RefSeq; WP_010969312.1; NC_003047.1.
DR   AlphaFoldDB; Q9R9N2; -.
DR   SMR; Q9R9N2; -.
DR   STRING; 266834.SMc01219; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   PRIDE; Q9R9N2; -.
DR   EnsemblBacteria; CAC46151; CAC46151; SMc01219.
DR   GeneID; 61603034; -.
DR   KEGG; sme:SMc01219; -.
DR   PATRIC; fig|266834.11.peg.2998; -.
DR   eggNOG; COG0438; Bacteria.
DR   HOGENOM; CLU_009583_1_0_5; -.
DR   OMA; IAPNFKR; -.
DR   UniPathway; UPA00958; -.
DR   PRO; PR:Q9R9N2; -.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Lipopolysaccharide biosynthesis; Reference proteome;
KW   Transferase.
FT   CHAIN           1..351
FT                   /note="Lipopolysaccharide core biosynthesis
FT                   mannosyltransferase LpsB"
FT                   /id="PRO_0000080297"
SQ   SEQUENCE   351 AA;  38662 MW;  9B436AB9DB82377A CRC64;
     MVDIRDVEVI APNFKQRLSG VTSTIIQLVP VQRALGQKIA VLGPGLPKSL PSVRFRDLIH
     LWKRPEGRPC RVWHARRNVE MLPAILLRDL LRMKLRIVFT SASQRRHTGW SKFLIRRMDA
     VIATSGRTAA YLDVPNTVIL HGIDTKRFQP PFDKTEAKKA LGLDPAKKFV GCFGRVRHQK
     GTDLFVDSMI ALLPCRPDWG AIVAGRATGP HLAFESELKE RVAKAGLADR ILFVGEHTNI
     PDWYRALDLF VAPQRWEGFG LTPLEAMATG VPVVATDVGA FSELVTGGSE ETGLIIAADD
     LKAMVDAAAA FMDDRPRLAA ASANGLARTS KNFAIEQEAR AIAAVYESLM R