ID   LPSD_RHIME              Reviewed;         343 AA.
AC   Q9R9N0;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Lipopolysaccharide core biosynthesis glycosyltransferase LpsD;
DE            EC=2.4.-.-;
GN   Name=lpsD; OrderedLocusNames=R01570; ORFNames=SMc01221;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=RCR2011 / SU47;
RX   PubMed=11157937; DOI=10.1128/jb.183.4.1248-1258.2001;
RA   Lagares A., Hozbor D.F., Niehaus K., Pich Otero A.J.L., Lorenzen J.,
RA   Arnold W., Puehler A.;
RT   "Genetic characterization of a Sinorhizobium meliloti chromosomal region
RT   involved in lipopolysaccharide biosynthesis.";
RL   J. Bacteriol. 183:1248-1258(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS core biosynthesis.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC       Glycosyltransferase 4 subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF193023; AAF06010.1; -; Genomic_DNA.
DR   EMBL; AL591688; CAC46149.1; -; Genomic_DNA.
DR   RefSeq; NP_385676.1; NC_003047.1.
DR   RefSeq; WP_010969310.1; NC_003047.1.
DR   AlphaFoldDB; Q9R9N0; -.
DR   SMR; Q9R9N0; -.
DR   STRING; 266834.SMc01221; -.
DR   CAZy; GT4; Glycosyltransferase Family 4.
DR   PRIDE; Q9R9N0; -.
DR   EnsemblBacteria; CAC46149; CAC46149; SMc01221.
DR   GeneID; 61603032; -.
DR   KEGG; sme:SMc01221; -.
DR   PATRIC; fig|266834.11.peg.2996; -.
DR   eggNOG; COG0438; Bacteria.
DR   HOGENOM; CLU_009583_0_3_5; -.
DR   OMA; IDGQPEV; -.
DR   UniPathway; UPA00958; -.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR028098; Glyco_trans_4-like_N.
DR   Pfam; PF13439; Glyco_transf_4; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Lipopolysaccharide biosynthesis; Reference proteome;
KW   Transferase.
FT   CHAIN           1..343
FT                   /note="Lipopolysaccharide core biosynthesis
FT                   glycosyltransferase LpsD"
FT                   /id="PRO_0000080298"
SQ   SEQUENCE   343 AA;  38726 MW;  4EC9939088019E05 CRC64;
     MKVMHIHFGT EGGAERFFVN LVNALHERGV EQRALIRPGR SWRKDLENGA TIYEGVFRRI
     SLSRFLLKWR MNRVLREFEP DVIMAWQLRA SRFMPAHAKA FRISRLGDYP EHLGYYTNVQ
     TLVCITPDMA AKVRELGWKR DIEVIANFTR ARPAPPVARA DLQTPADAFV VVGMGRFVKR
     KGFAGLIRAV KEVENTYLWL VGDGPEREQL EQLTDELGLR DRVRFTGWQT NAYGFLSAGD
     AFVINSSHEP LGNVCFEGWG AGKPTIASRA EGPSWVMTHE SDALMVDCGD DVGLAAAIRR
     LRDDPALRER LSAGGSETLR TRFSEKAITD AYLDLFDRGV AKR