ID   LPTD_ACTPJ              Reviewed;         778 AA.
AC   B0BPQ4;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=APJL_0981;
OS   Actinobacillus pleuropneumoniae serotype 3 (strain JL03).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=434271;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JL03;
RX   PubMed=18197260; DOI=10.1371/journal.pone.0001450;
RA   Xu Z., Zhou Y., Li L., Zhou R., Xiao S., Wan Y., Zhang S., Wang K., Li W.,
RA   Li L., Jin H., Kang M., Dalai B., Li T., Liu L., Cheng Y., Zhang L., Xu T.,
RA   Zheng H., Pu S., Wang B., Gu W., Zhang X.L., Zhu G.-F., Wang S.,
RA   Zhao G.-P., Chen H.;
RT   "Genome biology of Actinobacillus pleuropneumoniae JL03, an isolate of
RT   serotype 3 prevalent in China.";
RL   PLoS ONE 3:E1450-E1450(2008).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000687; ABY69539.1; -; Genomic_DNA.
DR   RefSeq; WP_012263039.1; NC_010278.1.
DR   AlphaFoldDB; B0BPQ4; -.
DR   SMR; B0BPQ4; -.
DR   EnsemblBacteria; ABY69539; ABY69539; APJL_0981.
DR   KEGG; apj:APJL_0981; -.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000008547; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           24..778
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_1000145514"
SQ   SEQUENCE   778 AA;  89835 MW;  CCEB21AE4DEAEFED CRC64;
     MKTRYSVLSV AMTAAFYTQY AQADLREQCL LGVPHFQGEE VTGDQTMMPI EIEADNAVIN
     QPKDATYTGD VAIKQGNRSL FADEVRVEQN GEQERRAFLK GSYRYQDNLV QAHGRDAAMD
     LGSETAELQN TEFQLVGRQG RGTAESGLFN HNKRILKNAT FTACLPNDNA WSIEGNEMIQ
     HIDEEYAEIW HARFKVLGMP VFYSPYLQFP IGDRRRSGLL IPNFHRSSKD GFAYSQPFYW
     NIAPNMDATI TPTYYSRRGW QISPEYRYLT KLGEGIVAGE YIGKDRLDEY RPDDNDRKRY
     LMHWRHNMSF LTGWRLYVDY TKVSDKRYFS DFDSEYGSST DGYATQQFKL GYYQPNYNLS
     ISGKKFQTFD ELDVGPYRVL PQIDFNYYND ELVKGGDFKL FAQTARFEND SKLMPKAWRF
     HVEPTLNFPL ANRYGSLNFE TKLYATHYLQ EKGSSKQADD MDKNVTRIIP QVKVDLQTVL
     EADKQLFKGF NQTFEPRVQY VYRPYKDQSN IGSGLNQSVS FGYDSALLQS DYFSLFNDRR
     YSGLDRISSA NLITAGGTNR FFNEKTGVEV FNFSIGQTYY LSPSKIDDLS QNSTTKRSSS
     WALESNWKFH RKWNWHGAYQ YDTRLNQTSL ANTSLQYKPS QDKLVQLSYR FASKDYINQN
     LRSNTYGQDI KQVGAVVGWE LTDRVAFMAS HYHDIALKKP VESQLSVNYN TCCWSANVYV
     ARKLTATPIG SPDTINDLYY DNKFGVNFEL RFGTNYSSGV RKMLKKGMIP YTEQYGIN