ID   LPTD_AERHH              Reviewed;         810 AA.
AC   A0KGU1;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=AHA_0945;
OS   Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / BCRC
OS   13018 / CCUG 14551 / JCM 1027 / KCTC 2358 / NCIMB 9240 / NCTC 8049).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=380703;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 7966 / DSM 30187 / BCRC 13018 / CCUG 14551 / JCM 1027 / KCTC
RC   2358 / NCIMB 9240 / NCTC 8049;
RX   PubMed=16980456; DOI=10.1128/jb.00621-06;
RA   Seshadri R., Joseph S.W., Chopra A.K., Sha J., Shaw J., Graf J., Haft D.H.,
RA   Wu M., Ren Q., Rosovitz M.J., Madupu R., Tallon L., Kim M., Jin S.,
RA   Vuong H., Stine O.C., Ali A., Horneman A.J., Heidelberg J.F.;
RT   "Genome sequence of Aeromonas hydrophila ATCC 7966T: jack of all trades.";
RL   J. Bacteriol. 188:8272-8282(2006).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000462; ABK37719.1; -; Genomic_DNA.
DR   RefSeq; WP_011704882.1; NC_008570.1.
DR   RefSeq; YP_855487.1; NC_008570.1.
DR   AlphaFoldDB; A0KGU1; -.
DR   SMR; A0KGU1; -.
DR   STRING; 380703.AHA_0945; -.
DR   PRIDE; A0KGU1; -.
DR   EnsemblBacteria; ABK37719; ABK37719; AHA_0945.
DR   KEGG; aha:AHA_0945; -.
DR   PATRIC; fig|380703.7.peg.947; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; DYSHLDW; -.
DR   Proteomes; UP000000756; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           30..810
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281585"
SQ   SEQUENCE   810 AA;  92094 MW;  8EFD169381AC7904 CRC64;
     MTKRTLGYSY PIALTISLVP ALTPAIVQAA PLTPPPATGI LDGLCYDYVP KIEKLAPGKD
     ANAQPVEVDA DRLEAKQGGT AVYQGDVKVR QGVRKFDSDY AELDQKSRDV IAIGNIYYND
     GQITVTSDKT LKSNLDTKNS ELEEGKYQVH GSPVRGSADR VTMTNNNQNI TLEGAQYTTC
     PPGQEVWTLK AGSIDIDQTE VFGEAWNASL WLYDYPVFYF PYINFPIKDE RKTGLLYPGY
     TQSSKNGMDI TQPFYWNIAP NYDATITSRF MDRRGLMEQV QFRYMPDPAH VGSLYFENLA
     NDKQYDETPS LNQAMSDGHR YLLNANHTSL FADNAMRVSL DYTKVRDRDY NYFNDFSPKV
     GTQVENQLQQ SLMAGYFQPN WNINTEVRTY QILLASAQQP HELMPRIDHN YYQQGSWYDL
     AWNTEITKFG YNNAQAIAQN QGGAYTGTRV YTAPTLTMPL INEAGYYLDS QYKLMYTRYD
     QEVPDNMSQT FVSRFTPENG NGVTLDEGII TRTLPSFRLK GGMTFERNQN WFGGDANQTL
     EPEFQYLYVP YKNQDNIGVY DSTSMRQDYY SLFSDRRYAG LDRISDSNRV SIGLTSRVYD
     EAGDERIRLA VAQAFDFVAP RVKLYPSETL TTNTRSPLSF EGDAKINEQW FAHAGAQYDV
     DQSRLSSANS ALEYRREKLI SQLNHRFVRD ANYDLENKGQ VTDLNQIGLL LTTPLNDQWH
     LYGGYYQELN QSVKSDRKVG LKYDSCCWSI NFNLEWVNTP DNVTMRPTSE RSLGIQFEMK
     GLGSVGTGSK GTSLDTEALP YIRPFNLRDQ