ID   LPTD_AERS4              Reviewed;         810 AA.
AC   A4SR03;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=ASA_3347;
OS   Aeromonas salmonicida (strain A449).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=382245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A449;
RX   PubMed=18801193; DOI=10.1186/1471-2164-9-427;
RA   Reith M.E., Singh R.K., Curtis B., Boyd J.M., Bouevitch A., Kimball J.,
RA   Munholland J., Murphy C., Sarty D., Williams J., Nash J.H., Johnson S.C.,
RA   Brown L.L.;
RT   "The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into
RT   the evolution of a fish pathogen.";
RL   BMC Genomics 9:427-427(2008).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000644; ABO91325.1; -; Genomic_DNA.
DR   RefSeq; WP_005311708.1; NC_009348.1.
DR   AlphaFoldDB; A4SR03; -.
DR   SMR; A4SR03; -.
DR   STRING; 382245.ASA_3347; -.
DR   EnsemblBacteria; ABO91325; ABO91325; ASA_3347.
DR   KEGG; asa:ASA_3347; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000000225; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           30..810
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_1000068452"
SQ   SEQUENCE   810 AA;  92195 MW;  5FFCCBE2ABDAAE58 CRC64;
     MTKWTLGYSY PIALTISLIP ALTPAIVQAA PLTPPPATGI LDGLCYDYVP KVEKLAPGKD
     ANAQPVEVDA DRLEAKQGGT AVYQGDVKVR QGVRKFDSDY AELDQKSRDV IAIGNIYYND
     GQITVTSDKT LKSNLDTKNS ELEEGKYQVH GSPVRGSADR VTMTNNNQNI TLEGAQYTTC
     PPGQEVWTLK AGSIDIDQTE VFGEAWNASL WLYDYPVFYF PYINFPIKDE RKTGLLYPGY
     TQSSKNGMDI TQPFYWNIAP NYDATITSRF MDRRGLMEQV EFRYMPDPAH VGSLYFENLA
     DDKQYDETPS LNEKLSDGHR YLLNARHTSL FADNAMRVSV DYTKVRDRDY NYFNDFSPKV
     GTQVENQLQQ SLMAGYFQQN WNLNTEVRTY QILLASAQQP HELMPRINHN YYHQGNWYDL
     AWNTEVTRFG YNNTQASAQN LGDAYTGTRV YTAPTLTMPL IDEAGYYLDS QYKLMYTRYD
     QEVPDNMSST FTKRFTPEGA SGVTLDEGII TRTLPSFRLK GGMTFERNQD WFGGDANQTL
     EPEFQYLYVP YKDQDNIGVY DSTTMRQDYY SLFSDRRYAG LDRISDSNRV SLGVTTRVYD
     QAGDERIRLA VAQAFDFVAP RVKLYPSESL ATNTRSPLSF EGDAKINEQW FAHAGAQYDM
     DQSEISSANS ALEYRREKLI SQLNYRFVRN ANYDLSNTNQ VADLNQVGML LTTPLNDQWH
     LYGGYYHDLD QGVKVDRKVG LKYDSCCWSI NFNLEWVNTP DNVTMRPTSE RSLGIQFEMK
     GLGSVGTGSK GTSLDTEALP YIRPFNLRDQ