ID   LPTD_BORA1              Reviewed;         797 AA.
AC   Q2KXA8;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 2.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=BAV0694;
OS   Bordetella avium (strain 197N).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=360910;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=197N;
RX   PubMed=16885469; DOI=10.1128/jb.01927-05;
RA   Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D.,
RA   Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A.,
RA   Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J.,
RA   Parkhill J., Temple L.M.;
RT   "Comparison of the genome sequence of the poultry pathogen Bordetella avium
RT   with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals
RT   extensive diversity in surface structures associated with host
RT   interaction.";
RL   J. Bacteriol. 188:6002-6015(2006).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM167904; CAJ48300.1; -; Genomic_DNA.
DR   RefSeq; WP_039051446.1; NC_010645.1.
DR   AlphaFoldDB; Q2KXA8; -.
DR   SMR; Q2KXA8; -.
DR   STRING; 360910.BAV0694; -.
DR   EnsemblBacteria; CAJ48300; CAJ48300; BAV0694.
DR   GeneID; 41392602; -.
DR   KEGG; bav:BAV0694; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_4; -.
DR   Proteomes; UP000001977; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   Pfam; PF04453; LptD; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           21..797
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_5000077345"
FT   REGION          23..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   797 AA;  89058 MW;  1FAD323014714CED CRC64;
     MHTIRCLILS ALSVAGAAQA QGSQDAAPAG RQPVGSVASP GLEMPGLRLS PGLRVRKLTE
     DQMPAFMEAD DMSGEPSAEL LLKGNAQVRR VDGVIKGDSI HYDDATSEVE VKGNARILRD
     ATLVTGPSAR INLNTYSGDI DKPNFWIGAS GGTARAEHAD IFSRSQMRLT DVYYSGCPCE
     KPSWYIKATS LDLDVDENEG VARNGVLYFK DVPILASPYL TFPIRKERKS GFLLPTYGTS
     SKTGLDISVP YYFNLAPNYD ATLISRYMGK RGLQLGGDFR YLGYSYAGSV SGTYLPNDRD
     AGFDRYMYRL THKQYLGSGF YTDWDISGVS DDNYYRDMTT LGLNTASTTY LPRQGRVGWS
     SNYWQTYVQV YKYRTLQDPD APIVPPYDKE PEIFLQGARY DWNGFDVRMD STAVRFRRPL
     FLGNRIGQEG ERLEAYPTIA YPIVRAGWYF TPKAGLNYTQ YHTSWFNQDW NRLGSLAPYR
     GTESRTLPIV SLDTGMTFER PTTLFGKDST QTLEPRLYYL RVPYRNQSAL PVYDTSLADF
     SFEQAFQENI YTGGWDRIAN ANQLTVGLTT RWLDASTGFQ RVALSAAQRL YFEDQRVTLP
     GETPRENVRS DFLVGASAAL TDTLTTDLAA QYNPYDNNWS RGLVSARWTP QRQTTLALAY
     RYQRDPISNI SYAPRGQNQV TLAFQWPFTQ RWYGVGRVDY AIRSDTGGVV GASDSARVTQ
     AIAGLEYKGD CCWTGRVVFQ RYAVAANDAN TAVFFQLELT GLGALGTDPL KLLDKSIPGY
     QPVSQPTPAG TTFERYE