LPTD_BURCH
ID LPTD_BURCH Reviewed; 786 AA.
AC A0KAD4;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN OrderedLocusNames=Bcen2424_2711;
OS Burkholderia cenocepacia (strain HI2424).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=331272;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HI2424;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P.,
RA Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., LiPuma J.J., Gonzalez C.F.,
RA Konstantinidis K., Tiedje J.M., Richardson P.;
RT "Complete sequence of chromosome 1 of Burkholderia cenocepacia HI2424.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000255|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC Rule:MF_01411}.
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DR EMBL; CP000458; ABK09461.1; -; Genomic_DNA.
DR RefSeq; WP_011546173.1; NC_008542.1.
DR AlphaFoldDB; A0KAD4; -.
DR SMR; A0KAD4; -.
DR KEGG; bch:Bcen2424_2711; -.
DR HOGENOM; CLU_009039_0_0_4; -.
DR OMA; DYSHLDW; -.
DR OrthoDB; 100018at2; -.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR Pfam; PF04453; LptD; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Signal.
FT SIGNAL 1..39
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT CHAIN 40..786
FT /note="LPS-assembly protein LptD"
FT /id="PRO_5000165002"
FT REGION 767..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 768..786
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 86936 MW; E9CE6230DD1A12B2 CRC64;
MPPKPLFPNV FPGDGAPRKR RLALALLAVP GLVPAVSYAQ LSGAAAQPQP LDSPWDLRLA
PQLEDHPLKD GAKPAAFVIA DHTSGTAEQD LAAKGSAELR RGDAVVKADA IHYDQDTDMA
DAYGQVKVIN GGTSFAGPEA HLKIEANQGF MTAPKYHFNV TGGSGSAERV DMVDNERSVF
VNGTYTACQC STNPAWYIKG SRFDFDTGAD EGTARNGVLF FQGVPIFASP WMTFPLSGER
RSGLLPPTFS MNSSNGFELS LPYYFNIAPN RDLTLTPRII SRRGVMTEAT FRYLSPSYSG
TFTANYLPDD RLAHRNRYAI YWQHQQNFGG GFGGYVYYNK VSDNTYPEDL GSANQFINGT
QTLYQQEAGL TYNNGPWSVL ARYQHWQTLP PSIAPYSREP QLNVKYTKYN VGGFDFGAEA
DYSRFRITTA DATEGDRIVF NPYISYGVYG PGYFVVPKVQ YHFASYDLNY LSSTTPNSPK
RFTESIPTVT FDTGLIFDRS VRLFGQDFIQ TLEPRLYYVY TPYRDQSNAP LFDTAESDFG
LAEIYQPNTF VGNDRIADAN RITAGLTSRF IDPRTGDERA RFVIAQQYYF ADQRVTLNPG
QAAVLARHSD LIVGAALKLG SGFMSETAFQ YNQNNNQLVK SSVGFGYSPG ERRVINVGYR
YTRANTTLDN QPINQFLVSA QWPLTRRLYA IGRFNYDLAG DRVVDGLVGL QYDADCWALG
VGVQRAANGI NSSGQQNSST RFMMQLTLKG LSTVDNGLVS AFRAGVPGYT PLPPPPPPMS
RFSNYE
