ID   LPTD_BURTA              Reviewed;         787 AA.
AC   Q2T117;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=BTH_I0575;
OS   Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 /
OS   E264).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=271848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264;
RX   PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA   Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA   DeShazer D.;
RT   "Bacterial genome adaptation to niches: divergence of the potential
RT   virulence genes in three Burkholderia species of different survival
RT   strategies.";
RL   BMC Genomics 6:174-174(2005).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000086; ABC38923.1; -; Genomic_DNA.
DR   RefSeq; WP_009892916.1; NZ_CP008785.1.
DR   AlphaFoldDB; Q2T117; -.
DR   SMR; Q2T117; -.
DR   PRIDE; Q2T117; -.
DR   EnsemblBacteria; ABC38923; ABC38923; BTH_I0575.
DR   KEGG; bte:BTH_I0575; -.
DR   HOGENOM; CLU_009039_0_0_4; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000001930; Chromosome I.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   Pfam; PF04453; LptD; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..39
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           40..787
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281596"
SQ   SEQUENCE   787 AA;  86451 MW;  294FEC803DEE96A9 CRC64;
     MPRKTLLPLV PACDAAPRRK RLAAALLAVP GLVPAVSQAQ LSGAAAEPQT FGSPWDLRLA
     PQLDEHPQKQ GGKPATFVLA DHTGGTADQD LAAKGSAEIR RGNAVVKADA IHYDQDTDMA
     DAYGKVTVAN GGTTFSGPEA HLKVEANQGF MTTPKYHFTA TGGSGSAERV QLLDSERSVF
     TNGTYTGCQC STNPAWYIRG SEFDFDTGAD EGVARNGVLF FQGVPLFGSP WLTFPLSGER
     RSGFLPPTFS PFSSTNGIEV SLPYYFNIAP NRDLTITPHI ISKRGIFTQA TFRYLSTNYS
     GALTGEYLPD DRIAHRNRYA IFWQHQQNFG NGFGGYIYYN KVSDNLYPEE LGSTNQFVNG
     IQTVYQQEAG LTYNDGPWSV LGRYQHWQTL PPAVAPYGRE PQLNVKYAKY NVGGFDFGAE
     ADYSRFRITT ADQPEGDRVM FNPYVSYGLY GPGYFFVPKA QLHIASYDLT TTTGGVPDQA
     KRFTYSIPTL SLDTGLVFDR SVRLFGQDYI QTLEPRLFYV YTPYRNQSNA PLFDTAVSDF
     GLAEIFTPNT FVGNDRIADA NRLTAALTTR FINPATGDER ARFVIAQQYY FTDQRVTLLP
     TEAPATARHS DLILGASVKL GAGFASETAF QYNVDNNQLV KSSVGFGYSP GERRVINVGY
     RYTRQNPTLS NEPINQILMS AQWPLTRRLY AVGRLNYDLA SSRVVDGLVG FQYDADCWAF
     GVGVQRYANG LNTSGQQNSS TRVLAQLVLK GLTSIDNGLV TAFRAGVQGY TPLPPAPAPL
     SRFSNYD