ID   LPTD_COLP3              Reviewed;         771 AA.
AC   Q47VK1;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=CPS_4523;
OS   Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio
OS   psychroerythus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Colwelliaceae; Colwellia.
OX   NCBI_TaxID=167879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=34H / ATCC BAA-681;
RX   PubMed=16043709; DOI=10.1073/pnas.0504766102;
RA   Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X.,
RA   Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M.,
RA   Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A.,
RA   Zhou L., Davidsen T.M., Wu M., Huston A.L., Lewis M., Weaver B.,
RA   Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.;
RT   "The psychrophilic lifestyle as revealed by the genome sequence of
RT   Colwellia psychrerythraea 34H through genomic and proteomic analyses.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000083; AAZ25223.1; -; Genomic_DNA.
DR   RefSeq; WP_011045252.1; NC_003910.7.
DR   AlphaFoldDB; Q47VK1; -.
DR   SMR; Q47VK1; -.
DR   STRING; 167879.CPS_4523; -.
DR   EnsemblBacteria; AAZ25223; AAZ25223; CPS_4523.
DR   KEGG; cps:CPS_4523; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_6; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000000547; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           26..771
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281599"
SQ   SEQUENCE   771 AA;  87875 MW;  ACD3474F1F6FAE4C CRC64;
     MFFSRTLSFT LVALLVVCLS QKAHANVEQK SQSPETRLMQ CPLPEFDDIA IGIPEVVDST
     IRISSSQASI QQDQIALFNG SVILVDKGQK IIADQLSFNR LKMQIEAIGN IHYQGKQINI
     FADKLSASKI DKSTEMTAAS YQLDGNPGHG KAGKLSINSD GMMSLVDSTF TTCLQEVPDW
     QIKASEINLS AKGDFGEAYH AQFRVLDVPV FYVPYFSFPI SKERLTGFLY PELSTSSSLG
     IEFTAPFYWN IAENYDATIT PRYMSERGTQ LQTEFRYLMD QQSGKIDLEY LNKDKKIKTN
     DDPRYLARFQ HIGTFSEDFR AYIDYTTISD DNYLVDIGSK QYNSNDAYLY QIGELAYFGE
     QWQATLQLQD FEVLGDHQSS YKTLPHLELS AQQPLNFLSG QFELYSEMTN FQPSEKDQVS
     ANRYHVEAGF TFPITRPSWF LNSEVKLMHT YYQQDNISAG SSLEETVDRT LPKVRIHAGV
     NFDRQLLAFG QSYRHTLEPQ LQYLYVPDED QSNIGLYDTT ILQDDFHGIF RDTRYSGLDR
     IAAANQFTWG ITSRLLDEEN LEIIRVSLGR IQYLGENNTD LANDALLTDN GGIDNKQSSV
     AADLFYRINH QWQVSGDIQY NTLEDFTNKG QVNLDYQINK YNLIQLNHRY TRNVSGDSLE
     QASLLTSIAI NENWAFVGRL TQDLQQDRSL ESYAGFQYES CCWAVRIAYQ RHINSNLDAA
     SFVSEGREQF DTGISIKLII KGLDGKQSAI GTQEMFDKSI FGYKRPYYLQ N