ID   LPTD_CUPPJ              Reviewed;         810 AA.
AC   Q475Q4;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=Reut_A0497;
OS   Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Cupriavidus necator
OS   (strain JMP 134)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=264198;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JMP134 / LMG 1197;
RX   PubMed=20339589; DOI=10.1371/journal.pone.0009729;
RA   Lykidis A., Perez-Pantoja D., Ledger T., Mavromatis K., Anderson I.J.,
RA   Ivanova N.N., Hooper S.D., Lapidus A., Lucas S., Gonzalez B.,
RA   Kyrpides N.C.;
RT   "The complete multipartite genome sequence of Cupriavidus necator JMP134, a
RT   versatile pollutant degrader.";
RL   PLoS ONE 5:E9729-E9729(2010).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; CP000090; AAZ59879.1; -; Genomic_DNA.
DR   RefSeq; WP_011296686.1; NC_007347.1.
DR   AlphaFoldDB; Q475Q4; -.
DR   SMR; Q475Q4; -.
DR   STRING; 264198.Reut_A0497; -.
DR   EnsemblBacteria; AAZ59879; AAZ59879; Reut_A0497.
DR   KEGG; reu:Reut_A0497; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_4; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..49
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           50..810
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281631"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          54..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   810 AA;  90726 MW;  C5F5E5B54C069579 CRC64;
     MTEQRRSPNK RANKPPALSG LSSRTGRLPA SALRPLVLAM AGLSVGAHAQ MSSSAVPDID
     QTESVVETAP EVPLAPPVSG ELVPRLAEPA KTTQPGESPP AFVSGDRLTG YNERGVVLEG
     NAELRRGGAV VKGDKLTYDQ DTDEAFAHGN ARVSRGGALA VGPEARMKVE ANEGYMLSPD
     YYFQQTGGTG KAERIDFIDK DRSVIKRATY TTCSPDNADW YFSARQLDLD SDREVGVAYG
     GVLHFFDVPI AGAPVFSFPL TDERRSGFLS PLFGYGSKSG LDVTLPYYFN IAPNRDLTLY
     PRIMTSRGFM LGGDYRYIGQ GYSGRLRAEI LPDDRQTNSN RWSYSFQHTQ NLAKGLNAYL
     NLNRVSDDRY PDDLTRTVAQ STQRQYIQEG GVTYNWQDFT VLARVQKFQT LLPSGPSYER
     EPQLNGKYIR YDLGGFDVQV EADYTRFRIP LTSTGFQQPQ GERMFVQPTI SYPIVRPGWY
     ATPKVIFNAT QYQMEPQSNT PTAQNNFSRT VPTFSFDSGM TFERDAPTMS RVFGVNYLQT
     LEPRLFYVYT PFRDQSQFPL FDTVQSDFGY GQIFSENPFT GYDRVADNNK LTAGLTTRLI
     EADTGIERFR GTIAQRYDFS GQRVQINGTL PDPKAGSSDL LAATTIQLFR GYYLDAGIQY
     NPDSEHINYS NLAFAWRPEP RKLLNVGYRY RRATSVTDNT AIDQFEISGQ WPITQRAYGI
     GRFAFDRNAN QMVDALAGLE YAADCWVGRV VYQRYRNTTQ GYTGRIFLQV EFRGLSKIGS
     NPLDILRLNV PGYEPVTAKP VPTTQFDHYE