ID   LPTD_HAEDU              Reviewed;         779 AA.
AC   Q7VKZ9;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=HD_1704;
OS   Haemophilus ducreyi (strain 35000HP / ATCC 700724).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=233412;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=35000HP / ATCC 700724;
RA   Munson R.S. Jr., Ray W.C., Mahairas G., Sabo P., Mungur R., Johnson L.,
RA   Nguyen D., Wang J., Forst C., Hood L.;
RT   "The complete genome sequence of Haemophilus ducreyi.";
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; AE017143; AAP96464.1; -; Genomic_DNA.
DR   RefSeq; WP_010945493.1; NC_002940.2.
DR   AlphaFoldDB; Q7VKZ9; -.
DR   SMR; Q7VKZ9; -.
DR   STRING; 233412.HD_1704; -.
DR   EnsemblBacteria; AAP96464; AAP96464; HD_1704.
DR   KEGG; hdu:HD_1704; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; DYSHLDW; -.
DR   Proteomes; UP000001022; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           24..779
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000020280"
SQ   SEQUENCE   779 AA;  90732 MW;  1D526F1A3085641E CRC64;
     MKIRYSVLST FIISALYSQD TQANLKHQCL LRVPHFAGEE ITADQLNMPI EIEADRAVIN
     QPKEANYSGN VTIKQGNRSI FADNVRIEQQ APQHRKAFLI GRYQYQDNLI QAEGHNALLD
     LQSKDAEVAN TTYQLVGRQG RGEAESGQFT PQTRRLKNAS FTACLLNDNA WSIEANEMVQ
     HIKAGYAEMW HARFKIFDVP IFYSPYLQFP LGDQRRSGIL TPKLYHSTKD GLIYSQPFYW
     NIAPNMDATF TSNYYSRRGW QINPEFRYLT ALGQGILAGE YLANDRLDTY RPKDMNDRRY
     LFHWRHNMSF LTDWHLDVDY TNVSDRRYFS DFDSSYGNVT DGYALQHFKL GYYQPQYNLS
     ISGKDFHTFD SFDNVKPYRV LPQIDFNYYQ DQFLKDSRFS FFAQIARFEN DSKSMPNAWR
     FHAEPIINIP FVNHYGSLNF ETKLYASHYQ QQKGENQTAE EVKKQLTRII PQVKLDFQTV
     LEADKSLFSG FKQILEPRLQ YVYRPYRDQS EIGSKSHESV GLGYDSALLQ TDYYSLFNDR
     RYSGLDRISS ANLITAGAST RFFNKKTGEE VFNISVGQTY YLRPSRVDSL AIDSTADRSS
     SWSVESNWRF QPKWNWHASY QYDTRLHKSS LANMSLQYKP STENVFQLNY RYVNEDYINQ
     NLSFNRYGQD IKQIGGMIGW NLTDKVAIMA SHYRDIALKK AVETQLSLNY NTCCWSANLY
     VARQLTTTPI GAKDSIRNFY YDNKFGINFE LRFGHDYSSG MHKMLSKGIL PYVEQYGIN