ID   LPTD_HAES1              Reviewed;         781 AA.
AC   Q0I1T9;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=HS_0205;
OS   Haemophilus somnus (strain 129Pt) (Histophilus somni).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=205914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=129Pt;
RX   PubMed=17172329; DOI=10.1128/jb.01422-06;
RA   Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O.,
RA   Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N.,
RA   Xie G., Inzana T.J.;
RT   "Complete genome sequence of Haemophilus somnus (Histophilus somni) strain
RT   129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus
RT   influenzae Rd.";
RL   J. Bacteriol. 189:1890-1898(2007).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000436; ABI24483.1; -; Genomic_DNA.
DR   RefSeq; WP_011608358.1; NC_008309.1.
DR   AlphaFoldDB; Q0I1T9; -.
DR   SMR; Q0I1T9; -.
DR   STRING; 205914.HS_0205; -.
DR   EnsemblBacteria; ABI24483; ABI24483; HS_0205.
DR   KEGG; hso:HS_0205; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_2_0_6; -.
DR   OMA; DYSHLDW; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           25..781
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281610"
SQ   SEQUENCE   781 AA;  91058 MW;  F3931601166C68D4 CRC64;
     MKKNYYTVLS LSILTALYST SSQANLQQQC LIGVPHFQGE IVQGDPNELP VYIEADHAKM
     NQSTHAQYEG NVNVKQGNRH LTAGMIEIEQ HGKDNAKRYA YAKNGFDYKD NLIQLNGDNA
     KIHLDSKDAN IQDADYQLVG RQGRGTADEV ELREHYRVMK NATFTSCLPN SDAWSIEAKE
     MRQHIQEEYA EMWHARFKVS GIPIFYTPYL QLPIGDRRRS GLLIPKAGIS TRHGYWYAQP
     FYWNIAPNFD ATFTPKYMSH RGWQLNAETR YLTRIGEGKF VVEYLKTDRH SDSLNTARSR
     HLFYWGHNSH FLKDWRLNVN YTKVSDKHYF NDFESEYGNS TDGYVDQQAS ISYYQPNYNL
     SISAKQFQIF DKVDIGPYRA LPQIDFNYYR NEIANGLVDF SLFSQVVRFD NDSALMPTAW
     RFHIEPSLTF PLSNRYGSLN IETKLYATRY LQKRGKGENA EEIKKTVNRV LPQIKLDFQT
     VLANRQSFIE GYTQTLEPKF QYLYRPYKDQ SDIGLKQQNN DYLGFGYDST LLQQDYFSLF
     RDRRYSGLDR IVSANQITLG GTTRFYDKNA NERFNLSIGQ IYYLKDSRTD NNPQNMAQGR
     SSSWSLESNW RINSKWNWRG SYQYDTHLNQ TSLANTVLEY NSEKNNLIQL SYRYVNQSYI
     DQNLIGKNTY GQSIKQLGMT TAWELTDHWT LVGRYYQDLA LKKPVEQYLG IQYNSCCWSI
     GVGARRYVTN RANQRNDEVL YDNSLSLTFE LRGLSPSDHK NNIDEMLKKG KLPYIKAFSL
     Y