ID   LPTD_IDILO              Reviewed;         757 AA.
AC   Q5QVP0;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000255|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000255|HAMAP-Rule:MF_01411}; Synonyms=imp, ostA;
GN   OrderedLocusNames=IL2229;
OS   Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Idiomarinaceae; Idiomarina.
OX   NCBI_TaxID=283942;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-735 / DSM 15497 / L2-TR;
RX   PubMed=15596722; DOI=10.1073/pnas.0407638102;
RA   Hou S., Saw J.H., Lee K.S., Freitas T.A., Belisle C., Kawarabayasi Y.,
RA   Donachie S.P., Pikina A., Galperin M.Y., Koonin E.V., Makarova K.S.,
RA   Omelchenko M.V., Sorokin A., Wolf Y.I., Li Q.X., Keum Y.S., Campbell S.,
RA   Denery J., Aizawa S., Shibata S., Malahoff A., Alam M.;
RT   "Genome sequence of the deep-sea gamma-proteobacterium Idiomarina
RT   loihiensis reveals amino acid fermentation as a source of carbon and
RT   energy.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:18036-18041(2004).
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01411}.
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DR   EMBL; AE017340; AAV83061.1; -; Genomic_DNA.
DR   RefSeq; WP_011235456.1; NC_006512.1.
DR   AlphaFoldDB; Q5QVP0; -.
DR   SMR; Q5QVP0; -.
DR   STRING; 283942.IL2229; -.
DR   EnsemblBacteria; AAV83061; AAV83061; IL2229.
DR   KEGG; ilo:IL2229; -.
DR   eggNOG; COG1452; Bacteria.
DR   HOGENOM; CLU_009039_0_0_6; -.
DR   OMA; DYSHLDW; -.
DR   OrthoDB; 100018at2; -.
DR   Proteomes; UP000001171; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01411"
FT   CHAIN           21..757
FT                   /note="LPS-assembly protein LptD"
FT                   /id="PRO_0000281612"
SQ   SEQUENCE   757 AA;  86670 MW;  79EE38224657475B CRC64;
     MLQRFITSLM LLPFPGSALA ALQNQDAPQH MTCTVAQPTE SMIGAVQLQK TEAGTIGVES
     RSAEILANEK AYFTGNVIIQ RNGQWLSTSK ATIDQQRGEI LASDGITFND GYLSVTGDSL
     SLDLNDDQAK LYNSDYRLQN HNARGHAELL SLSRQEVLLQ DSSFTTCPGE TPAWQLRAER
     IEINETSDFG EAWHARFELF DVPVLYLPYF NFPLSDARKT GLLYPTFDSS SNSGFEVEVP
     YYFNIAPNMD ATIAPVYMSE RGTMMKGEYR YLFEQNAGQF NLEYLGNDDT RIANKKRYLW
     HVQHSAQINQ DLSFYLDATE ISDDNYLNDF GSDFAGRADT HLYRVAQLDY DNENWTAQLR
     TEDYELIGDY RSPYRTLPQL SIDYNTGDFT GFSASLYNEL TYFQNQDQTR EYATRAHIEP
     SIQYRFEKPA FDTEAELSYL YTRYWQESPD ANITEEVTRT LPRARVRARL HLERAIELGD
     SQYRQTLSPQ IQYLYVPYEN QQNIGIYDTS LLQDDYHGLF RSRRFSGLDR IAEANQITYG
     VSSSLFTQNE REVLRASIGQ IYNINDSRTQ LFASDEETTT SSNSEWVADI NWAVDENWSI
     RSSIQYDTEL NTTRKSQTAV EFRKDESNLI QVSHRTATNI LNNDIEQVGT QAVWSANSRW
     QVASNVFYDL THDRLNDAMV GIQYSSCCWA LRVSAYRRIN RDLEPAFSAT QINGETQFDN
     GISIQFIISG LASDSSGLIN MLEKSTYGYR RPFYLSN